جست‌وجوی استاد و پژوهشگر

• Neurobiology
• Neurodevelopmental Disorders
• Genetics
• +۶ مورد دیگر

Dr Lachlan Jolly serves as Head of the Neurobiology Research Group and First 1000 Days Fellow at the University of Adelaide, affiliated with the School of Biomedicine within the Faculty of Health and Medical Sciences. His research focuses on understanding the genetic, molecular, cellular, and developmental processes underlying brain development to provide targeted treatments for neurodevelopmental disorders (NDDs). Dr Jolly's research program centers on three major projects: (1) Nonsense Mediated mRNA Decay (NMD) pathways, where he discovered NMD factor mutations cause NDDs and is developing NMD-targeted therapies for nonsense mutation diseases; (2) Protein degradation mechanisms, where he investigates ubiquitin-dependent protein de-ubiquitination in brain development with over 20 years of expertise; and (3) Discovery of disease-causing splice variants using CRISPR dCas9 technology to study silent genes in patient-derived cells. His work addresses the challenge that neurodevelopmental disorders affect approximately 2% of the global population, with genetic mutations as the primary cause in developed countries. With around 1,000 genes and 10,000 variants implicated in NDDs, Dr Jolly's strategy targets 'points of convergence' between disorders of different genetic origins, particularly cellular degradation pathways including NMD and protein ubiquitylation. Dr Jolly's research has significant clinical implications, as nonsense mutations account for 13% of all genetic diseases, and haploinsufficiency affects approximately 3,000 genetic conditions. His NHMRC Ideas Grant (2021-24) and Sanfilippo Foundation funding (2021-2022) support the development of biomarkers, biosensors, and FDA-approved molecules to modify NMD pathways. His research outputs demonstrate a strong focus on translational science, with recent publications examining proteomic analysis of brain development, deubiquitinating enzymes in NDDs, and neural differentiation in genetic disorders. Dr Jolly has established global collaborations with clinicians and scientists and developed diagnostic tools for patients with neurodevelopmental conditions. As an active researcher with publications spanning from 2004 to 2025, Dr Jolly maintains dual office locations at the Adelaide Health and Medical Sciences building (Eighth Floor) and the Clarence Reiger Building at the Women's & Children's Hospital (Second Floor), reflecting his integration of basic science with clinical applications.

Nina Pollakمشاهده پروفایل

پژوهشگر ارشد

• Diagnostic technology
• Vaccine development
• Molecular biology
• +۶ مورد دیگر

Dr. Nina Pollak is a Research Fellow at the Centre for Bioinnovation within the School of Science, Technology and Engineering at the University of the Sunshine Coast (UniSC), Queensland, Australia. As an Associate Fellow of the Higher Education Academy (AFHEA), she serves as a Higher Degree by Research (HDR) Supervisor, mentoring graduate students in molecular biology, biotechnology, genetics, and microbiology. Her academic credentials include a PhD, MSc, and BSc from KFU Graz, complemented by professional qualifications in auditing and business compliance from CAL. Dr. Pollak's research focuses on innovative applications at the intersection of molecular biology and practical healthcare solutions. Her primary interests include diagnostic technology development, vaccine research (particularly for koala Chlamydia), synthetic biology tools, and rapid pathogen detection systems. She has pioneered work in isothermal amplification techniques, multiplex diagnostic platforms, and molecular computing approaches that enable field-deployable testing solutions for arboviruses and other infectious diseases. Her research directly addresses critical public health challenges in resource-limited settings through development of rapid, cost-effective diagnostic tools. Analysis of Dr. Pollak's publication record reveals a consistent trajectory focused on molecular diagnostics and synthetic biology applications. Her recent work demonstrates increasing specialization in rapid, field-deployable diagnostic platforms for arboviruses like Zika and dengue, with particular emphasis on recombinase polymerase amplification (RPA) technologies coupled with lateral flow detection. She has made significant contributions to multiplex diagnostic systems, SNP detection for insecticide resistance, and molecular computing using deoxyribozymes and RNA aptamers. Her research consistently bridges fundamental molecular biology with practical applications for public health challenges. As an HDR Supervisor, Dr. Pollak has mentored graduate researchers including Madeeha Ahmed, whose doctoral work focused on dengue virus diagnostics and insecticide resistance detection in Aedes mosquitoes. Her collaborative approach is evident through extensive co-authorship across multiple institutions, particularly with Joanne Macdonald, David McMillan, and other researchers at UniSC. Her work has secured research funding that supports the development of diagnostic technologies with real-world applications in infectious disease surveillance and control. Dr. Pollak operates within the Centre for Bioinnovation at UniSC, where she leads research efforts focused on developing innovative biotechnology solutions for disease detection and prevention. Her laboratory work integrates molecular biology techniques with engineering approaches to create practical diagnostic platforms. She collaborates extensively with the Thompson Institute and other research centers at UniSC, contributing to interdisciplinary efforts in health innovation. Her research team focuses on translating laboratory discoveries into field-applicable technologies that can be deployed in resource-limited settings worldwide.

• Plant Molecular Biology
• Plant Pathology
• Plant Biochemistry
• +۴ مورد دیگر

Dr. Shamila Abeynayake serves as an Honorary Research Fellow in the Department of Ecological Plant and Animal Sciences at La Trobe University, Melbourne. Her research bridges molecular plant science and ecological applications, with emphasis on stress physiology and pathogen detection. Her primary research interests include plant molecular biology, plant pathology, and plant biochemistry, focusing on molecular mechanisms of cold acclimation in grasses, proanthocyanidin biosynthesis in white clover, and stress-induced metabolic changes in aquatic plants. She integrates genomics, metabolomics, and field ecology to address agricultural challenges. Analysis of her 14 publications (2008-2024) reveals three dominant research trajectories: molecular diagnostics for plant pathogens (e.g., CRISPR-based Xylella detection), stress adaptation in perennial grasses, and specialized metabolite production in tropical flora. Recent work increasingly emphasizes field-deployable tools and Sri Lankan biodiversity. Dr. Abeynayake maintains extensive collaborations across Australian and Sri Lankan institutions, with co-authors spanning molecular biologists, virologists, and ecologists. Her work on Azolla stress responses and cinnamon essential oils demonstrates strong regional focus on South Asian ecosystems.

• Electrochemistry
• Electrochemiluminescence (ECL)
• Electrochemical simulations
• +۴ مورد دیگر

Dr. Samridhi Bajaj serves as a MOBIUS Postdoctoral Research Officer in the Biochemistry department at La Trobe University's La Trobe Institute for Molecular Science (LIMS) in Melbourne. Her work focuses on advancing electrochemiluminescence (ECL) for point-of-use biosensing applications. Education: PhD in Biochemistry and Chemistry, La Trobe University (2021-2025) Master of Chemical Science, La Trobe University (2019-2020) Bachelor of Science, University of Delhi (2015-2018) Dr. Bajaj pioneered "annihilation bipolar electrochemiluminescence" during her doctoral research, establishing core expertise in ECL, electrochemistry, and electrochemical simulations. Her current work develops ultra-sensitive, low-cost biosensors using single-board computers and photodetectors, bridging fundamental science with practical point-of-care diagnostics. Her research spans electroanalytical chemistry, simulation modeling, and programming for sensor development. Her recent publications demonstrate a consistent focus on enhancing electrochemical detection methodologies, particularly through voltammetric techniques and ECL-based sensing strategies. Key advancements include improved kinetic measurement protocols and novel baseline correction methods for cyclic voltammetry. Scientific Contributions: Development of annihilation bipolar ECL for molecular detection FTACV applications for homogeneous kinetics analysis Diffusional baseline fitting techniques for voltammetry As a postdoctoral researcher in the ARC Industry Transformation Hub for Molecular Biosensors (MOBIUS), Dr. Bajaj collaborates with industry partners to translate fundamental electrochemical research into portable diagnostic technologies. Her technical proficiency spans electrochemical instrumentation, programming, and low-cost sensor fabrication. Dr. Bajaj operates within the La Trobe Institute for Molecular Science (LIMS), contributing to the MOBIUS Hub's mission of creating point-of-use molecular biosensors through interdisciplinary collaboration between chemistry, engineering, and industry partners.

• Marine Sciences
• Fish Physiology
• Aquaculture
• +۵ مورد دیگر

Associate Professor Luis Afonso is a distinguished researcher and educator at Deakin University's School of Life and Environmental Sciences, where he serves as Deputy Director of the Bachelor of Science program. With over a decade of experience at Deakin and prior research leadership at the British Columbia Centre for Aquatic Health Sciences in Canada, his career spans significant contributions to marine sciences, fish physiology, and innovative applications of nanotechnology in environmental contexts. His research interests encompass fish stress physiology, reproductive biology, aquaculture, and the emerging field of nanotoxicology. Afonso employs an integrative approach combining immunology, endocrinology, and multi-omics techniques to investigate critical fish health issues. More recently, his work has expanded into developing nanobiosensors for environmental monitoring and assessing the impacts of nanomaterials on aquatic ecosystems and agricultural systems. The analysis of his 15 most recent publications reveals a strong interdisciplinary focus bridging marine biology, environmental science, and nanotechnology. His research demonstrates consistent innovation in developing novel methodologies for environmental monitoring while addressing practical challenges in aquaculture and sustainable agriculture. His work on nanoparticle impacts spans multiple biological systems from cellular models to whole organisms across aquatic and terrestrial environments. Excellence in Teaching Award (2015) for innovation in teaching program design Excellence in Teaching Award (2014) for empowering learners for future jobs and skills Excellence in Teaching Award (2012) for outstanding performance Deakin University Excellence in Research Award (2012) Afonso has supervised over 20 doctoral students across diverse research areas including fish physiology, nanotoxicology, and agricultural nanotechnology. His leadership extends to multiple institutional roles including Faculty HDR Coordinator (2022-2023) and Director of International Research Training (2016-2019). His research program benefits from extensive national and international collaborations with researchers in India, Japan, USA, and Australia, as well as industry partners such as Petuna Ltd., Nautilus Collaboration, and Tassal Group.