جست‌وجوی استاد و پژوهشگر

Bradley D. Olsenمشاهده پروفایل

استاد

• Polymer Science
• Materials Engineering
• Soft Condensed Matter Physics
• +۴ مورد دیگر

Bradley D. Olsen is a full professor in the Department of Chemical Engineering at the Massachusetts Institute of Technology (MIT), where he leads research at the intersection of polymer science, soft matter physics, and bioengineering. His work focuses on designing materials for critical applications in biotechnology, hemostasis, and sustainable polymer development while advancing fundamental understanding of polymer network mechanics and self-assembly. Education: Ph.D. in Chemical Engineering, University of California Berkeley (2007) S.B. in Chemical Engineering, Massachusetts Institute of Technology (2003) Olsen's research spans protein-based materials, block copolymer phase behavior, and mechanochemical hydrogels. He has pioneered methods for quantifying polymer network topology, developing hemostatic nanoparticles, and creating bio-inspired materials for selective biomolecular transport and medical applications. His recent publications emphasize data-driven approaches to polymer characterization and educational outreach in materials science. Scientific Awards: American Physical Society (APS) Fellow (2023) Fulbright Amazonia Scholar (2023) Alexander and I. Michael Kasser Chair in Chemical Engineering (2021) ACS Macro Letters Young Investigator Award (2021) MIT Committed to Caring Honor (2019) AIChE Owens Corning Early Career Award (2019) APS Dillon Medal (2018) Kavli Emerging Leader in Chemistry (2017) ACS Polymer Division Fellow (2016) Camille Dreyfus-Teacher Scholar (2015) Alfred P. Sloan Research Fellow (2014) NSF Career Grant (2013) NIH Postdoctoral Fellowship (2008-2009) Hertz Fellow (2003-2007) Barry M. Goldwater Scholarship (2002) Olsen has received significant grant support including NSF Career (2013) and AFOSR (2012) awards. His teaching activities include innovative international outreach like the 2025 soccer-themed science camp in Brazil. The Olsen Group at MIT explores advanced materials with applications ranging from trauma care to sustainable polymers.

Raphael Franziniمشاهده پروفایل

دانشیار

• Drug Discovery
• Medicinal Chemistry
• Bioorthogonal Chemistry
• +۳ مورد دیگر

Raphael Franzini serves as Associate Professor of Medicinal Chemistry at the University of Utah, actively contributing to the Biological Chemistry PhD Program. His research pioneers innovative chemical approaches for therapeutic development, with dual focus on DNA-encoded library technologies and bioorthogonal drug delivery systems. His educational foundation includes an M.S. from the Swiss Federal Institute of Technology (Lausanne) and a Ph.D. from Stanford University. This training underpins his group's multidisciplinary methodology combining organic synthesis, bioconjugation, computational modeling, and advanced imaging techniques. Dr. Franzini's research program centers on two transformative areas: First, advancing DNA-encoded library screening through computational integration to identify leads for challenging targets like Tankyrase and Sirtuin 6, with recent work addressing false negatives in machine learning prediction. Second, developing novel bioorthogonal release chemistry using isonitrile-tetrazine reactions for spatiotemporally controlled drug activation, validated in zebrafish models. His group emphasizes both technological innovation and therapeutic translation, with chemistry designed to minimize off-target effects in solid tumors. Analysis of his 15 most recent publications reveals escalating integration of computational methods with experimental library screening, alongside refinement of bioorthogonal release kinetics. The work spans chemical biology, medicinal chemistry, and pharmaceutical sciences, with growing emphasis on machine learning for library data interpretation and in vivo validation of drug-release systems. Dr. Franzini maintains an active research laboratory that provides comprehensive training in cutting-edge drug discovery methodologies. His group culture prioritizes both scientific innovation and researcher development, with projects spanning from fundamental reaction kinetics to therapeutic applications. The lab's infrastructure supports organic synthesis, molecular imaging, and computational analysis for advancing precision therapeutics.

Sharon Rozovskyمشاهده پروفایل

استاد

• Oxidative Stress
• Protein Quality Control
• ERAD Pathway
• +۵ مورد دیگر

Sharon Rozovsky is a Professor in the Department of Chemistry and Biochemistry at the University of Delaware's College of Arts & Sciences, where she leads research on oxidative stress response mechanisms and protein quality control pathways. Her work bridges biochemistry, chemical biology, and structural biology with direct implications for understanding neurodegenerative diseases and viral pathogenesis. Her academic foundation includes a B.S. from Tel Aviv University (1994) and a Ph.D. from Columbia University (2000), establishing her expertise in protein dynamics and redox biochemistry. These credentials underpin her innovative approaches to studying cellular stress responses. Rozovsky's research program centers on selenoproteins—proteins containing the rare amino acid selenocysteine—and their critical roles in endoplasmic reticulum (ER) stress resolution. She investigates how membrane-bound selenoproteins like Selenoprotein S and K regulate the ER-associated degradation (ERAD) pathway, with recent work revealing their surprising autoproteolytic activity and involvement in SARS-CoV-2 replication. Her lab pioneers chemical tools including expressed protein ligation and advanced 77Se NMR spectroscopy to characterize these systems at molecular resolution. Analysis of her 2021-2025 publications shows dominant themes in selenoprotein structure-function relationships, ER stress mechanisms, and viral interactions, alongside methodological innovations in cryo-EM grid technology and NMR. This body of work demonstrates consistent focus on redox biochemistry with expanding applications in virology and structural biology. No major scientific awards or fellowships were explicitly documented in the available materials, though her research impact is evident through high-impact publications and methodological contributions. She directs the active Rozovsky Research Group, mentoring graduate students and postdoctoral researchers in biochemical and biophysical techniques. Her laboratory operations are supported by competitive funding including an NSF CAREER award (2011) focused on selenoprotein reactivity, reflecting sustained recognition of her innovative research program.

Matthew R. Jonesمشاهده پروفایل

دانشیار

• Nanoparticle Assembly
• Plasmonics
• Metamaterials
• +۵ مورد دیگر

Matthew R. Jones is an Associate Professor in the Department of Chemistry at Rice University and holds the Gene and Norman Hackerman Junior Chair and Norman Hackerman-Welch Young Investigator titles. He joined Rice in 2017 after postdoctoral research at UC Berkeley under Paul Alivisatos and a PhD at Northwestern University under Chad Mirkin. His research focuses on systems-level nanoparticle assembly, plasmonics, and metamaterials, with applications in energy storage and biomedicine. Jones has pioneered techniques like 4D-STEM for catalytic nanoparticles and developed adaptive materials via strain-controlled synthesis. Education: B.S. in Materials Science and Biomedical Engineering (Carnegie Mellon University), Ph.D. in Chemistry (Northwestern University as an NSF Fellow). Key awards include the Packard Fellowship (2018) and NSF CAREER Award (2022). His lab hosts over 20 graduate students and postdocs, with notable advisees including Bukky, Zhihua Cheng, and Saxton. Research emphasizes interdisciplinary approaches: combining in-situ microscopy, ligand engineering, and computational modeling to control nanoparticle behavior. Recent studies include strain-preserved nanocatalysts (2024) and chiral superlattices (2024). Collaborations span Rice’s Center for Nanoscale Imaging Sciences and the Electrochemical Society. Lab: Jones Research Group Grants: NSF CAREER, Packard Fellowship, Rice Seed Award Publications: Over 50 peer-reviewed articles, including Science Advances (2024) and Nature Communications (2023)

Geoffrey Tranmerمشاهده پروفایل

دانشیار

• Medicinal Chemistry
• Drug Discovery
• Organic Synthesis
• +۴ مورد دیگر

Geoffrey Tranmer is a Tenured Associate Professor in the College of Pharmacy at the University of Manitoba. His research integrates medicinal chemistry, drug discovery, and synthetic organic methodologies, with a focus on flow chemistry and targeted cancer therapies. NSERC Post-Doctoral Fellow, University of Cambridge Post-Doctoral Fellow, Princeton University PhD in Organic Chemistry, University of Guelph BSc (Hons) in Chemistry, Brock University His research explores: Development of flow chemistry techniques to enhance synthetic organic methods Lead generation and optimization in drug discovery Bioconjugation strategies for chemical biology applications Targeted cancer therapies leveraging hypoxia-activated prodrugs Recent publications highlight his work in neurodegenerative disease drug design, biomarker discovery, and sustainable synthesis technologies. Scientific Awards CIHR Project Grant (2024-2029) NSERC Discovery Grant (2023-2028) CIHR Bridge Grant (2022) NSERC Alliance Grant (2020) NSERC Engage Grant (2017) Research Manitoba New Investigator Operating Grant (2017) Dr. Tranmer's industrial experience at Merck Frosst and academic leadership at Manitoba position him uniquely to bridge chemistry-biology-industry collaborations. His lab actively trains graduate students in cutting-edge synthesis platforms.

Adam Caparcoمشاهده پروفایل

استادیار

• Agricultural Biotechnology
• Environmental Biotechnology
• Enzyme Immobilization
• +۶ مورد دیگر

Adam Caparco is the DiPietro Assistant Professor of Chemical Engineering at Northeastern University, with a 25% joint appointment in the Department of Chemistry and Chemical Biology. He leads the Caparco Research Group, focusing on agricultural and environmental biotechnology, enzyme immobilization, and protein assemblies. His work integrates plant virology, nanotechnology, and molecular engineering to address sustainability challenges in agriculture and environmental remediation. He is a member of the Institute for Plant-Human Interface and holds affiliations with Northeastern’s College of Engineering and School of Arts and Sciences. Education: B.S. in Chemical and Biomolecular Engineering from UCLA (2015), Ph.D. from Georgia Tech (2020) under Julie Champion and Andreas Bommarius, followed by a USDA NIFA Postdoctoral Fellowship at UC San Diego under Nicole Steinmetz. His research spans plant immunoengineering, biomanufacturing in plants, and protein-based nanomaterials for bioremediation. Research Interests Plant excretion pathways for pathogen defense and environmental remediation Design of immobilized enzymes for green chemical synthesis Plant virus nanoparticles for nucleic acid delivery and immunity modulation Multifunctional protein engineering for sustainable agriculture Recent articles highlight advancements in plant virus-based delivery systems, enzyme immobilization strategies, and nano-enabled precision agriculture. Awards include the USDA NIFA Postdoctoral Fellowship. Caparco advises graduate and undergraduate researchers, including Julia Hilgemberg Merlin (PhD ChE), Olha Bereziuk (PhD CCB), and Paul Carter (PhD ChE). He collaborates widely and seeks to expand interdisciplinary research in plant biotechnology. Labs/Teams: Caparco Research Group (EXP 420 lab, EXP 530B office) and the Institute for Plant-Human Interface.

Hyun-soon Chongمشاهده پروفایل

استاد

• Organic synthesis
• Medicinal chemistry
• Bioconjugate chemistry
• +۷ مورد دیگر

Hyun-soon Chong is a Professor of Chemistry at the Lewis College of Science and Letters , Illinois Institute of Technology. The Chong group focuses on interdisciplinary research spanning organic synthesis, medicinal chemistry, and nuclear medicine to develop targeted therapeutics for cancer and neurodegenerative diseases. Education : B.S. from Kyung Hee University, Ph.D. from the University of North Texas Research interests include: Organic synthesis using aziridinium ions Development of bifunctional chelators for radiotherapy/imaging Bioconjugate chemistry for antibody-drug conjugates Targeted cancer therapies and diagnostics Nuclear medicine applications with isotopes like Cu-64, Y-90, and Lu-177 Key publication trends show expertise in chelation chemistry, bioconjugation, and radiopharmaceutical development. The group has advanced aziridinium ion-based methodologies and created novel agents with preclinical efficacy. Labs/teams: The Chong group specializes in synthetic strategies for enantiomerically enriched molecules and biomedical chelators. Contact: chong@illinoistech.edu

Sabine Glasl-Tazreiterمشاهده پروفایل

مدرس

• Phytochemistry
• Biodiscovery
• Ethnomedicinal Plants
• +۴ مورد دیگر

Sabine Glasl-Tazreiter is a Lecturer at the University of Vienna's Faculty of Life Sciences , specifically within the Department of Pharmaceutical Sciences and its Division of Pharmacognosy . Her office is located in room 2E 412 on the 4th floor at Josef-Holaubek-Platz 2, Vienna, Austria (1090). Contact details include telephone number +43-1-4277-55207 and email sabine.glasl@univie.ac.at . Principal research focus: Phytochemistry & Biodiscovery Specialization: Secondary metabolites from ethnomedicinally used plants across Europe, Mongolia, and Latin America Key techniques: Isolation of bioactive compounds, structural elucidation, pharmacological evaluation Quality control expertise: Macroscopic/microscopic identification, chemical analytics Recent publications highlight her work in: 2024 - Development of the VOLKSMED Database for Austrian folk medicine wound healing plants 2025 - Advanced mucociliary clearance research in respiratory systems 2023 - Innovations in optoacoustic imaging technology 2019 - Structure-function analysis of phycobiliproteins for medical imaging 2017 - Phytochemical characterization of Latin American antidiabetic plants

Saidul Islamمشاهده پروفایل

مدرس

• Prebiotic Chemistry
• Organic Chemistry
• Chemical Origin of Life
• +۳ مورد دیگر

Dr Saidul Islam is a Lecturer in Chemistry at King's College London, part of the Department of Chemistry within the Faculty of Natural, Mathematical & Engineering Sciences. He specializes in prebiotic chemistry, focusing on understanding the chemical origins of life and systems chemistry. His research explores pathways for nucleic acids, peptides, and organic cofactors under prebiotic conditions. Joined King's College London in 2022 as part of the Department's expansion program. Previously held postdoctoral positions at Queen Mary University of London and UCL. Teaching roles include leading 'Organic Chemistry 2' and guiding postgraduate research. Research interests center on prebiotic systems chemistry, including catalytic peptide ligation, chemoselective synthesis, and the role of cyanide in early metabolism. The Islam Group investigates chemical pathways that could have led to life's emergence on early Earth, employing synthetic organic chemistry and advanced analytical techniques like NMR spectroscopy. Key contributions include studies on pantetheine synthesis, peptide ligation mechanisms, and the enrichment of prebiotic molecules via heated gas bubbles. His work bridges organic chemistry with the origins of biological systems, addressing fundamental questions about life's chemical beginnings.

• Bioorganic Chemistry
• Chemical Biology
• Organic Chemistry
• +۵ مورد دیگر

Prof. Dr. Norbert Sewald, Chair of Organic and Bioorganic Chemistry at Bielefeld University, is a leading figure in Bioorganic Chemistry , Chemical Biology , and Enzymatic Halogenation . As head of the Organic and Bioorganic Chemistry Group at the Center for Biotechnology (CeBiTec), he drives research on natural products and drug conjugates. Full Professor, Bielefeld University (since 1999) Founding Coordinator, International Graduate School of Chemistry and Biochemistry (2001-2003) Chairman, Institute of Biochemistry and Bioengineering at CeBiTec (2006-2008) Dean, Department of Chemistry (2008-2011) Chairman, Max-Bergmann-Kreis e.V. (since 2010) Coordinator, Marie Skłodowska-Curie Training Networks (MAGICBULLET, 2015-2018; Magicbullet::reloaded, 2020-2023) His research focuses on halogenases for mild peptide bromination, cryptophycin-based tumor targeting , and bioactive natural products from African flora. Collaborative projects span antiplasmodial agents , antibacterial compounds , and neurodegenerative disease inhibitors . Recent work highlights include: Enzymatic halogenation cascades Click-to-release drug conjugates Fluorescent probes for amyloid detection Key affiliations: Faculty of Chemistry Center for Biotechnology (CeBiTec) European Peptide Society (Scientific Affairs Officer, 2016-) Leibniz Institute of Plant Biochemistry (Scientific Advisory Board, 2010-2017)

Franziska Thomasمشاهده پروفایل

استادیار

• Protein Folding
• Peptide Design
• Protein Aggregation Mechanisms
• +۶ مورد دیگر

Jun.-Prof. Dr. Franziska Thomas is a Junior Professor at the Institute of Organic Chemistry, Heidelberg University, leading an active research group at the interface of organic chemistry, biochemistry, and biophysics. Her work centers on understanding protein folding mechanisms and their implications for biological function. Dr. Thomas established her independent research group at Georg-August-Universität Göttingen in June 2015 before moving to Heidelberg University in February 2020. She was offered her current tenure track position at Heidelberg on April 26, 2019. Her research program has two primary focuses: (1) designing peptide scaffolds with catalytic activity using de novo designed components that can be chemically synthesized and modified, and (2) studying protein aggregation mechanisms relevant to neurodegenerative diseases such as amyotrophic lateral sclerosis. She employs small, well-characterized self-assembling peptides to create novel materials and understand disease pathways. Analysis of her publication record reveals consistent advancement in peptide and protein engineering, with recent work emphasizing WW domains, β-sheet miniproteins, and innovative solid-phase synthesis techniques. Her research bridges fundamental protein science with applications in materials engineering and disease mechanism understanding. Her work has received significant funding including: The excellence cluster 3DMM2O for the project 'Design of Structured Adhesion Miniproteins for Tissue Engineering' The Deutsche Forschungsgemeinschaft for the research grant 'The WW-domain scaffold as a model system for the de novo design of miniaturized phosphate receptors, phosphatases and sulfatases' Dr. Thomas actively mentors a large research team including 11 PhD students and 2 Master's students, with numerous past students who have successfully completed their theses. She teaches courses including 'Chemische Biologie' and 'OC-Z6 Synthese und Retrosynthese' and participates in seminar series such as IMSEAM and 3DMM2O. The Thomas Lab maintains strong collaborative connections with multiple research groups including the Kivala, Kemerink, Blasco, Klein, Comba, and Gräter groups, reflecting an interdisciplinary approach to peptide and protein science.

• Structural Biology
• Biophysics
• Notch Signaling
• +۷ مورد دیگر

Wendy R Gordon serves as an Associate Professor in the Structural Biology and Biophysics department at the University of Minnesota Medical School. Her research program bridges structural biology, biophysics, and translational medicine with significant funding from NIH sources including the National Cancer Institute and National Institute of General Medical Sciences. Dr. Gordon leads multiple active research projects focused on mechanobiology, protein engineering, and cancer therapeutics. Dr. Gordon's research interests center on understanding molecular mechanisms of cell surface receptors, particularly the Notch signaling pathway, and developing innovative tools for studying cellular mechanics. Her work spans structural biology approaches to characterize protein-DNA interactions, mechanotransduction mechanisms, and receptor regulation. She has developed novel technologies including HUH-Tags for protein-DNA labeling and tension sensors for measuring cellular forces. Her research has significant implications for cancer immunotherapy, particularly in engineering protein modulators of Notch activation for CAR T-cell therapy. Analysis of Dr. Gordon's recent publications reveals a strong focus on three interconnected research themes: 1) molecular mechanisms of Notch signaling and receptor regulation, 2) development of innovative tools for protein-DNA conjugation and cellular mechanotype measurement, and 3) applications of these technologies to cancer biology and immunotherapy. Her work demonstrates increasing integration of structural biology with functional cellular assays and therapeutic applications, particularly in tumor microenvironment and immunotherapy contexts. Dr. Gordon currently leads or collaborates on seven major research projects totaling millions in NIH funding. Her active grants include: LUMICKS C-trap for Mechanistic Studies of Biological Systems (as PI), Engineering Protein Modulators of Notch Activation for CAR T-cell immunotherapy (as CoI), Viral vector technology for cell type specific gene delivery (as CoI), Decoding mechanotransduction mechanisms of cell-surface receptors (as PI), and the Center for Multiparametric Imaging of Tumor Immune Microenvironments (as CoI). These projects reflect her expertise spanning structural biology, mechanobiology, and translational applications. Dr. Gordon's laboratory operates at the intersection of structural biology and cellular mechanobiology, with strong collaborations across the University of Minnesota campus including with cancer researchers, bioengineers, and clinicians. Her team develops and applies cutting-edge technologies including single-molecule techniques, protein engineering approaches, and high-throughput cellular mechanotype measurement systems to address fundamental questions in receptor biology with therapeutic implications.

Michael Willisمشاهده پروفایل

استاد

• Organic Synthesis
• Catalysis
• Sulfur Functional Groups
• +۴ مورد دیگر

Michael Willis is Professor of Chemistry at the University of Oxford and Fellow of Lincoln College, leading the Willis Research Group with expertise in catalytic organic synthesis. His work bridges academic innovation and industrial pharmaceutical applications through novel sulfur chemistry methodologies. His educational trajectory includes: Undergraduate studies at Imperial College London PhD at University of Cambridge under Professor Steve Ley Postdoctoral research at Harvard University with Professor David Evans Research centers on catalytic sulfur functionalization, particularly using DABSO as a sulfur dioxide surrogate to develop sulfonamide/sulfonimidamide synthesis routes. His group pioneers enantioselective desymmetrization methods and heterocyclic cross-coupling techniques, emphasizing industrial applicability in drug discovery. Key themes include energy-efficient catalysis and sustainable chemistry approaches to complex molecule synthesis. Analysis of recent publications (2021-2023) reveals sustained innovation in sulfur reagent development, with increasing focus on photocatalysis and radical-based transformations for sulfonamide diversification. The work demonstrates strategic progression from fundamental reagent discovery (DABSO) to complex target synthesis with pharmaceutical relevance. Award recognition includes: 2015 Pfizer, AstraZeneca, Syngenta Process Chemistry Research Award 2014 Royal Society of Chemistry Catalysis in Organic Chemistry Award 2008 AstraZeneca Award in Synthetic Organic Chemistry The Willis Group maintains active pharmaceutical industry collaborations while developing next-generation catalytic methods. Current projects focus on expanding sulfur pharmacophore applications and improving synthetic efficiency for agrochemical targets through novel catalytic manifolds.

Giancarlo Pascaliمشاهده پروفایل

دانشیار

• Radiopharmaceutical Sciences
• Radiochemistry
• Automation in Radiopharmaceutical Production
• +۷ مورد دیگر

Dr. Giancarlo Pascali is a Conjoint Associate Professor at the School of Chemistry, UNSW Sydney , and Radiochemistry Team Leader at ANSTO's Camperdown cyclotron site. With a PhD in "Innovative Biomedical Technologies" from the University of Lecce (2004), he has held research positions at IFC-CNR , NIH , and GMP facilities in Milan and Pisa. His expertise spans radiochemical methods , radiopharmaceutical development , and microfluidic automation for nuclear medicine production. Education: PhD in Innovative Biomedical Technologies, University of Lecce (2004) BSc in Chemistry, University of Pisa (2001) Research interests focus on M 3 : Molecules, Methods, Machines . In Molecules , he designs radiopharmaceuticals for cancer , dementia , and inflammatory diseases . For Methods , his work explores photochemistry , electrochemistry , and mechanochemistry to label biomolecules with 18 F and other isotopes. Under Machines , he pioneers microfluidic systems for automated radiochemistry, emphasizing safety and process reliability . Editorial & Leadership Roles: Editorial Board Member of Nuclear Medicine and Biology , Contrast Media & Molecular Imaging , and Current Radiopharmaceuticals Executive Board of ANZSNM , ARTnet , and ASMI Asia-Oceania Director and iSRS2025 Chair for SRS

Glenn Sammisمشاهده پروفایل

استاد

• Synthetic Organic Chemistry
• Radical Fluorination
• Natural Product Synthesis
• +۳ مورد دیگر

Glenn Sammis is a Professor at the Department of Chemistry, University of British Columbia. His research focuses on synthetic organic chemistry, particularly radical fluorination, natural product synthesis, and the application of sulfur(IV) fluorides in pharmaceutical and industrial contexts. B.S. in Chemistry, Stanford University (1999) Ph.D. in Organic Chemistry, Harvard University (2004) NIH Postdoctoral Fellow, Princeton University (2004-2006) His group develops innovative methods for fluorine atom transfer, radical relay cyclizations, and electrochemical processes to address synthetic challenges in pharmaceuticals and natural products. Recent work emphasizes the use of sulfuryl fluoride and thionyl fluoride in one-pot reactions. Publications highlight trends in radical fluorination, SuFEx chemistry, and electrochemical synthesis. Over 25 years, 15+ students and postdocs have advanced careers in academia, industry, and healthcare.