جست‌وجوی استاد و پژوهشگر

Michael Schlierfمشاهده پروفایل

استاد

• Membrane protein folding
• Protein-DNA interactions
• Regulatory DNA and RNA conformations
• +۵ مورد دیگر

Prof. Michael Schlierf is a Professor for Molecular Biophysics at B CUBE – Center for Molecular Bioengineering, Technische Universität Dresden (TU Dresden), where he has led his research group since 2017. Previously, he served as a Junior Group Leader at B CUBE from 2010-2017, following postdoctoral work at the University of Illinois at Urbana-Champaign. His research focuses on conformational dynamics of biomolecules, specifically membrane protein folding, protein-DNA interactions during DNA replication and recombination, and regulatory DNA and RNA structures. His group develops and applies advanced single-molecule spectroscopy and microscopy techniques to observe biomolecular dynamics at unprecedented resolution. Current methodological expertise includes molecular bioengineering, single-molecule FRET, TCSPC, magnetic tweezers, and optical tweezers. Prof. Schlierf's publication record spans high-impact journals including Nature Communications, Science Advances, and PNAS, with recent work emphasizing membrane protein biogenesis, DNA recombination mechanisms, and innovative single-molecule methodologies. His research program demonstrates consistent evolution from fundamental protein folding studies to complex biological systems. BMFTR Go-Bio initial (2025-2026) DAAD PROCOPE German-French collaboration (2025-2026) EFRE-JTF aCOS validation funds (2024-2026) DFG projects on outer membrane protein biogenesis, replication initiation, and relaxase dynamics Previous funding from BMBF, DFG Clusters of Excellence (Physics of Life), and Boehringer Ingelheim Foundation Prof. Schlierf actively supervises multiple PhD students and postdocs, with a track record of successful alumni who have secured positions in academia and industry. His group maintains an interdisciplinary environment that bridges physics, biology, and chemistry approaches to study fundamental biomolecular processes. The Schlierf Group operates within B CUBE – Center for Molecular Bioengineering at TU Dresden, with access to state-of-the-art single-molecule instrumentation and collaborative opportunities across the university's strong life sciences ecosystem. The group participates in teaching activities at the Center for Molecular and Cellular Bioengineering and contributes to graduate education through the Dresden International Graduate School for Interdisciplinary Life Sciences.

• Nucleotide Metabolism
• Genome Stability
• Cancer Biology
• +۵ مورد دیگر

Dr. Kasper Fugger serves as Senior Research Fellow at the UCL Cancer Institute and Visiting Scientist at the Francis Crick Institute, funded by Cancer Research UK RadNet. His research program investigates nucleotide metabolism's critical role in maintaining genome stability and preventing carcinogenesis. His educational background includes: PhD, University of Copenhagen (2010) MSc, University of Copenhagen (2005) BSc, University of Copenhagen (2002) Dr. Fugger's research focuses on cellular mechanisms that detoxify hazardous non-canonical nucleotides originating from environmental exposures, radiation, and metabolic processes. His lab specializes in understanding how failures in these pathways drive chromosomal instability in cancer, with particular emphasis on therapeutic targeting of nucleotide pool sanitization enzymes like DNPH1. This work bridges fundamental biochemistry with translational applications, employing CRISPR screening, structural biology, and high-throughput drug validation approaches. His publication record demonstrates significant impact in genome stability research, with recent work revealing FAT1's role in chromosomal instability (2025) and establishing DNPH1 as a major target for overcoming chemotherapy resistance (2021). These studies consistently appear in premier journals including Nature, Science, and Cell, reflecting both mechanistic depth and therapeutic relevance. Dr. Fugger actively collaborates with industry partners to translate discoveries into clinical applications, particularly in PARP inhibitor resistance mechanisms. His lab maintains strong international connections through projects like TRACERx and publications with multinational author teams. As a group leader, he oversees a dynamic research environment focused on nucleotide metabolism pathways, with opportunities for trainees to engage in both basic mechanism studies and translational drug development projects.

• Visual Arts
• Sculpture Techniques
• Ceramic Studies
• +۳ مورد دیگر

Céline Cadaureille is a Senior Lecturer at Jean Monnet University's Faculty of Arts, Letters, and Languages, where she leads research activities in the ECLLA Laboratory. She holds significant administrative responsibilities as Head of License 3 and coordinates interdisciplinary research seminars. Her academic trajectory includes a PhD in Art and Art Sciences from University of Toulouse Le Mirail (2009) and advanced training in Fine Arts from Toulouse School of Fine Arts. Her research explores three interconnected domains: Material practices in sculpture, ceramics, and molding techniques Bodily representations examining desire, mortality, and corporeal transformation Research-creation methodologies bridging academic and artistic practices She currently directs the 'Becoming Rocks' project (2025-2026) investigating mineral materiality through art-science collaborations. Publications since 2020 demonstrate consistent focus on: Material behaviors (viscosity, fragmentation, plasticity) Historical-contemporary dialogues in sculpture Pedagogical applications of research-creation Interdisciplinary approaches linking art with anthropology and thanatology Her work appears in edited volumes from Hermann and PUM presses, with frequent contributions to international conferences. Through ECLLA Laboratory, she leads projects combining: Artistic workshops with ceramicists and performers Theoretical study days on materiality International collaborations with institutions in Canada and Switzerland Recent initiatives include 'En sédimentation' (2025) exploring geological time through art, continuing her career-long investigation of material agency.

• Radiobiology
• Cell Biology
• Cancer Research
• +۵ مورد دیگر

Nuria Pastor Carrillo is a Full Professor in the Department of Cell Biology at the University of Seville, where she leads the Cell Culture and Radiobiology Research Group (BIO-120). Her academic career spans over three decades, during which she has established herself as a prominent researcher in DNA damage and repair mechanisms, with particular expertise in topoisomerase enzymes and their role in cancer biology. Her research interests encompass radiobiology, cancer therapeutics, DNA damage response mechanisms, and epigenetic regulation. Dr. Pastor Carrillo investigates how DNA topoisomerases function in chromosome segregation, the effects of epigenetic drugs on DNA damage pathways, and the development of novel anticancer strategies targeting neuroblastoma and other malignancies. Her work bridges fundamental molecular biology with translational cancer research. Analysis of her recent publication record (2010-2022) reveals a consistent research trajectory focused on DNA damage mechanisms, particularly examining how epigenetic drugs like 5-aza-2'-deoxycytidine cause DNA lesions that require specific repair pathways. Her work increasingly incorporates nanomedicine approaches for cancer therapy and has expanded into radiation biodosimetry through her participation in the European RENEB network. Dr. Pastor Carrillo currently leads multiple research projects including a contract studying MYCN in neuroblastoma stem cells and an R&D&I project optimizing differentiation processes in stem and tumor cells. She has received continuous funding through the BIO-120 Research Group incentives and has participated in numerous national and international collaborative projects throughout her career. Her laboratory, the Cell Culture and Radiobiology group, maintains active research programs in cancer cell biology, DNA repair mechanisms, and radiation response. Through her involvement with RENEB, her lab also contributes to the European capacity for radiation emergency response through biological dosimetry techniques.

Eleanor Scerriمشاهده پروفایل

استاد

• Archaeological science
• Human evolution
• Material culture
• +۹ مورد دیگر

Eleanor Scerri is a W2 Professor and Research Group Leader of the Human Palaeosystems Research Group at the Max Planck Institute of Geoanthropology in Jena, Germany. She is also a Reader at the Department of Prehistoric Archaeology at the University of Cologne and an Associate Professor in the Department of Classics and Archaeology at the University of Malta, her alma mater. Dr. Scerri obtained her PhD in Archaeology from the University of Southampton, jointly funded by the Royal Anthropological Institute and the Sutasoma Trust. Prior to her current position, she held prestigious fellowships including a Marie Skłodowska-Curie Actions Fellowship at the Max Planck Institute for the Science of Human History, a British Academy Fellowship at the University of Oxford with a Junior Research Fellowship at Jesus College, and a Fyssen Foundation funded postdoctoral fellowship at the University of Bordeaux. She received tenure in 2023 after winning a place on the Lise Meitner Excellence Programme with her 'Pan African Evolution Research Group'. Her research focuses on exploring the articulation between material culture, genetics, and biogeography to advance theoretical, methodological, and scientific understanding in human evolution and niche expansion. The Human Palaeosystems Group investigates deep time human-environment relationships to understand the dynamics of human bio-cultural evolution and ecosystem change, from the rise of our species until the beginning of agriculture. Her work centers on three key areas: the emergence and expansion of the human niche with its technological societal and ecological feedbacks, disease-culture co-evolution, and island colonization with ecosystem resilience and societal feedbacks. Her approach combines primary fieldwork with a range of modeling approaches using paleoecological and genetic data. Dr. Scerri's recent publications demonstrate a strong focus on human evolution in Africa and Southwest Asia, with particular attention to the Middle Stone Age, lithic technology, and human-environment interactions. Her work frequently addresses the complex population structure of early Homo sapiens in Africa and challenges simple out-of-Africa models, instead supporting structured metapopulation models of human origins. She has made significant contributions to understanding the role of tropical forests in human evolution and the dynamics of island colonization. Lise Meitner Excellence Programme (2023) Marie Skłodowska-Curie Actions Fellowship British Academy Fellowship Fyssen Foundation Postdoctoral Fellowship Dr. Scerri supervises undergraduate and postgraduate students at the University of Cologne, where she teaches undergraduate courses and supervises Masters projects. She leads several major research projects including the ERC StG funded IslandLab Project, which explores the transition from pristine natural systems to human dominated landscapes on Malta; the Disease-Culture Co-evolution project; and the Pan-African Evolution Project, which involves extensive fieldwork in West Africa investigating the deep human past in this region. The Human Palaeosystems Research Group conducts fieldwork programs across Africa and the Mediterranean, particularly in West Africa, Arabia, and Malta. The group's approach integrates archaeological, paleoenvironmental, and genetic data to test hypotheses about human evolution and the growth and impact of the human niche. Their work has significantly advanced understanding of human dispersals, population structure in Africa, and the complex evolutionary processes that shaped our species.