جستجوی استاد راهنمای دانشگاهی

• Nanomaterials Chemistry
• Electron Microscopy
• Electrocatalysis
• +۳ مورد دیگر

Dr. Lucy Gloag is a Lecturer at the Research School of Chemistry at the Australian National University (ANU), where she joined in 2024 after previously serving as a Lecturer at the University of Technology Sydney in 2023. Her research focuses on the development of advanced nanomaterials for energy applications, particularly in electrocatalysis and energy storage. Education: BSc/BCA and BSc(Hons) from Victoria University of Wellington, New Zealand PhD from the University of New South Wales (2018) on synthesis and characterization of Ru-based nanocatalysts Dr. Gloag is a nanomaterials chemist and electron microscopist specializing in the synthesis and characterization of nanomaterials for electrocatalytic applications. Her research addresses the fundamental question of how nanostructure can be used to enhance the performance of electrocatalysts . She employs solution-phase synthesis techniques to create nanoparticles with precise control over crystal structure, dimensions, and surface faceting, then correlates these structural features with electrocatalytic properties using transmission electron microscopy and electrochemistry. Her work spans energy conversion technologies, biomedical applications of nanoparticles, and advanced materials characterization. Analysis of her recent publications reveals a strong focus on single-atom catalysts, hierarchical nanostructures, and the relationship between nanomaterial structure and function. Her research spans both fundamental materials science and practical applications in energy conversion, with significant work on oxygen evolution reaction, hydrogen evolution reaction, and methanol oxidation electrocatalysts. She has also made notable contributions to biomedical applications of nanoparticles, particularly in magnetic particle imaging and Alzheimer's disease diagnostics. Scientific Awards: ARC Discovery Project Grant (2023) ARC Linkage Project Grant (2023) UNSW Science COVID19 Strategic Support Grant (October 2021) Dementia Australia Research Foundation – Yulgilbar Innovation Grant (2019-2022) Australian Postgraduate Research Scholarship (2015) AMN-7 Image Competition Finalist (2015) Dr. Gloag currently leads the ANU Futures Scheme 2.0 project (2024-2028) and has secured multiple competitive research grants, demonstrating strong research leadership. Her work involves extensive collaboration with researchers at UNSW and other institutions, particularly with Professors Richard Tilley and Justin Gooding. She has published 28 research outputs since 2015, with significant citation impact (h-index of 17). Her laboratory at ANU (Building 137, room 2.49) focuses on developing single atom and nanomaterials for energy storage and conversion technologies, continuing her trajectory as an emerging leader in advanced materials synthesis and electron microscopy characterization.

Eric W. Schmidtمشاهده پروفایل

استاد

• Natural Products Chemistry
• Biosynthesis
• Synthetic Biology
• +۵ مورد دیگر

Eric W. Schmidt is a Distinguished Professor of Medicinal Chemistry at the University of Utah, with adjunct appointments in Biological Sciences and Chemistry. His research focuses on natural products chemistry, biosynthesis, synthetic biology, and pharmaceutical applications of marine animal microbiomes. University of California, San Diego (BS, PhD) Research areas include: Biosynthesis in animals and their microbiomes Synthetic biology approaches to chemical engineering Drug design from marine natural products Metagenomic analysis of symbiotic relationships Neuroactive compound discovery Antibiotic development against resistant pathogens His lab has pioneered methods for: Biosynthetic gene cluster identification Heterologous expression in E. coli Enzymatic modification of peptides Chemical analysis of marine invertebrates Recent publications highlight discoveries in: Marine animal chemical defense mechanisms Evolution of biosynthetic pathways Antibiotic resistance profiling Ionic channel-targeting compounds Peptide macrocyclization techniques Lipid-polyketide biosynthesis continuum Email: ews1@utah.edu Honors include: Distinguished Professor recognition

• Neuroscience
• Neurodegenerative Diseases
• Alzheimer's Disease
• +۳ مورد دیگر

Hideyuki Takahashi is an Associate Research Scientist in the Department of Neuroscience at Yale University School of Medicine. He holds a PhD from Waseda University (2005) and has established himself as a prominent researcher in neurodegenerative diseases, particularly focusing on lysosomal biology and protein aggregation mechanisms. Dr. Takahashi's research primarily investigates the role of progranulin, TMEM106B, and other molecular players in neurodegenerative conditions including Alzheimer's disease, frontotemporal dementia, and tauopathies. His work spans multiple approaches from molecular and cellular neuroscience to animal models of disease. His recent publications demonstrate a strong focus on lysosomal dysfunction in neurodegeneration, with particular attention to how TMEM106B interacts with other proteins to influence disease progression. The research trends show increasing emphasis on therapeutic interventions targeting specific molecular pathways involved in protein aggregation and synaptic loss. ORCID: 0009-0004-4969-977X Dr. Takahashi maintains active collaborations with several leading researchers at Yale, most notably with Stephen Strittmatter (with whom he has 16 common publications), as well as Anita Huttner, Anthony Koleske, and Le Zhang. His research program appears well-integrated within Yale's neuroscience community, contributing significantly to our understanding of neurodegenerative disease mechanisms.

Jason Yiمشاهده پروفایل

استادیار

• Neuroscience
• Molecular Neuroscience
• Developmental Neuroscience
• +۶ مورد دیگر

Dr. Jason Yi is an Assistant Professor of Neuroscience at Washington University School of Medicine (WashU Medicine). His research focuses on understanding the molecular pathways that shape nervous system development and function, with particular emphasis on autism spectrum disorders (ASD). He leads the Yi Lab, which investigates the role of the ubiquitin ligase UBE3A in the brain and its implications for neurodevelopmental disorders. Dr. Yi received his BS in Biochemistry and Molecular Biology from Dickinson College in 2001 and his PhD in Pharmacology from Duke University in 2009. His laboratory is broadly interested in the molecular pathways that shape nervous system development and function, with the ultimate goal of understanding how dysfunction in these pathways contributes to disease. The current focus is on autism spectrum disorders (ASD), using genetic information from human patients to guide in vitro and in vivo experiments employing biochemical, genetic manipulation, cell biological, and microscopy techniques. Dr. Yi's research has significant clinical implications, particularly in understanding how UBE3A dysfunction relates to both Angelman syndrome (caused by lack of UBE3A activity) and autism (caused by excessive UBE3A activity). His lab discovered that a single phosphorylation event in UBE3A turns off its ubiquitin ligase activity, and that mutations in this site are linked to autism. This work bridges disease genetics with a mechanistic understanding of ASD neurobiology and aims to define developmental timepoints for ASD onset. Dr. Yi's research has been recognized with numerous prestigious awards: Ruth K. Broad Biomedical Research Foundation Predoctoral Fellowship (2006) F32 Kirschstein National Research Service Award (2011) Christina Castellana Postdoctoral Fellowship (2011-2014) The University of North Carolina Postdoctoral Award for Research Excellence (2015) Bridge to Independence Award, The Simons Foundation (2017) NARSAD Young Investigator Award, Brain and Behavior Research Foundation (2018) Whitehall Foundation Research Grant (2018) Alfred P. Sloan Foundation Research Fellowship (2019) Dr. Yi's research program is supported by significant grant funding from organizations including The Simons Foundation, Brain and Behavior Research Foundation, and the Whitehall Foundation. His work bridges basic molecular neuroscience with clinical implications for neurodevelopmental disorders, particularly autism spectrum disorders. Through his research, Dr. Yi is contributing to a deeper understanding of the molecular mechanisms underlying ASD, which may ultimately lead to new therapeutic approaches and interventions. The Yi Lab maintains a collaborative research environment focused on cutting-edge neuroscience techniques. The lab combines molecular, cellular, and genetic approaches to study UBE3A function and its role in neurodevelopment. Their work utilizes patient-derived genetic information to guide experimental approaches, ensuring clinical relevance to autism spectrum disorders. Dr. Yi is also actively involved in mentoring graduate students and postdoctoral fellows, contributing to the training of the next generation of neuroscientists.

Nika Danialمشاهده پروفایل

دانشیار

• Metabolic Biology
• Cancer Research
• Diabetes
• +۴ مورد دیگر

Dr. Nika Danial is an Associate Professor of Cell Biology at Harvard Medical School and the Department of Cancer Biology at Dana-Farber Cancer Institute. She leads the Danial Lab, investigating metabolic mechanisms that regulate cellular adaptation to stress, with a focus on fuel utilization in health and disease. Dr. Danial holds additional roles as Co-Director of the NCI-funded T32 Training Program in Cancer Chemical Biology and Metabolism. Her research integrates biochemistry, mouse models, and metabolomics to study metabolic contributions to cancer, diabetes, and neurological disorders. Education: PhD from Columbia University (1999), postdoctoral training at Harvard Medical School and Dana-Farber under Dr. Stanley Korsmeyer. Key research areas include mitochondrial dynamics, glucose metabolism pathways, and the interplay between inflammation and metabolic signaling. The lab has pioneered studies on how metabolic flexibility impacts disease progression in pancreatic islets, lymphoma subtypes, and neuronal excitability. Publications highlight discoveries in mitochondrial fatty acid oxidation regulation, urea cycle anti-inflammatory mechanisms, and metabolic signatures in cancer subtypes. Her work has implications for developing therapies targeting metabolic vulnerabilities in diseases like diffuse large B-cell lymphoma and type 1 diabetes. The Danial Lab emphasizes rigorous training for the next generation of scientists through mentorship programs and interdisciplinary collaboration.

Pia Vogelمشاهده پروفایل

استاد

• ATP Synthase
• Multidrug Resistance
• Ryanodine Receptor
• +۵ مورد دیگر

Pia Vogel is a Professor in the Department of Biological Sciences at Southern Methodist University (SMU), where she leads research on nucleotide-binding proteins using Electron Spin Resonance spectroscopy and molecular modeling. Her work focuses on elucidating structural mechanisms in ATP synthase, multidrug resistance transporters, and calcium channels with biomedical applications in cancer therapy and neurodegenerative diseases. Education: Ph.D., University of Kaiserlautern Dr. Vogel's research program investigates three interconnected domains: the rotary mechanics of FoF1-ATP synthase (particularly the external stalk subunit b-dimer), the structural basis of multidrug resistance in P-glycoprotein and MRPs, and ATP-regulated calcium release via ryanodine receptors. Her laboratory employs site-specific spin labeling, ESR spectroscopy, and computational modeling to resolve protein dynamics and interactions at molecular resolution, contributing to understanding energy transduction in ATP synthase and mechanisms of drug resistance. Analysis of her 15 most recent publications (2020-2025) reveals a dominant focus on developing and characterizing P-glycoprotein and BCRP inhibitors to overcome chemotherapy resistance in cancer. These studies integrate computational screening, ATPase assays, and cell-based models to evaluate inhibitor efficacy, with emerging applications in Alzheimer's research through amyloid-β transport studies. The work demonstrates consistent methodological synergy between biophysical characterization and therapeutic development. Dr. Vogel maintains an active research group supported by sustained funding, evidenced by continuous publication output and laboratory infrastructure. Her team employs multidisciplinary approaches spanning biophysics, biochemistry, and computational biology to address fundamental questions in membrane protein function. Her laboratory facilities in DLSB 221 include specialized Electron Spin Resonance instrumentation and dual Linux computing clusters for molecular dynamics simulations. The research environment supports collaborative projects extending her work into cancer therapeutics and neurodegenerative disease mechanisms through partnerships with clinical and computational researchers.

Sean J. Morrisonمشاهده پروفایل

استاد

• Stem Cell Biology
• Cancer Progression
• Metabolism
• +۳ مورد دیگر

Sean J. Morrison is the founding Director of the Children’s Medical Center Research Institute at UT Southwestern (CRI) and a Howard Hughes Medical Institute Investigator. He holds the Mary McDermott Cook Chair in Pediatric Genetics and the Kathryne and Gene Bishop Distinguished Chair in Pediatric Research. Dr. Morrison earned his B.Sc. in Biology and Chemistry from Dalhousie University (1991), a Ph.D. in Immunology from Stanford University (1996), and completed a postdoctoral fellowship in Neurobiology at Caltech (1999). Education: B.Sc. - Dalhousie University (Biology & Chemistry, 1991) Ph.D. - Stanford University (Immunology, 1996) Postdoctoral Fellowship - Caltech (Neurobiology, 1999) Research Interests: Dr. Morrison’s laboratory investigates the mechanisms that maintain adult tissues and how cancer cells exploit these processes to form tumors. His team compares stem cell and cancer cell replication mechanisms to develop novel regenerative medicine and anticancer therapies. Key areas include: Stem cell self-renewal and aging Metabolic regulation of hematopoietic stem cells Leptin Receptor+ stromal cell function Cancer progression and metastasis Proteostasis and niche biology Mechanotransduction in stem cell niches Publications reveal trends in stem cell metabolism, tumor heterogeneity, and niche dynamics across Science , Nature , and Cell . His work on retrotransposons in stem cell activation (2024) and β-adrenergic receptor inhibition in hematopoietic regeneration (2024) highlights emerging therapeutic targets. Awards & Recognitions: Dr. Morrison is an elected member of the U.S. National Academy of Medicine (2018), National Academy of Sciences (2020), and EMBO (2023). He received the Presidential Early Career Award (2003), MERIT Award from NIA (2009), and UT Southwestern’s Excellence in Postdoctoral Mentoring Award (2020). Mentorship & Leadership: Dozens of graduate students and postdoctoral fellows from his lab have secured academic leadership roles or industry positions. He served as President of the International Society for Stem Cell Research (2015–2016) and actively engages in public policy debates about stem cell research, including Michigan’s constitutional protections for regenerative medicine.

Anne Berit C. Samuelsenمشاهده پروفایل

دانشیار

• Polysaccharide Chemistry
• Pharmacognosy
• Carbohydrate Polymers
• +۴ مورد دیگر

Anne Berit C. Samuelsen serves as Associate Professor at the Department of Pharmacy, University of Oslo, where she also holds the position of Head of Education. Her academic foundation includes a Cand.pharm. degree and Dr.scient. doctorate, establishing her expertise in pharmaceutical sciences. Her research centers on polysaccharides from natural sources—particularly higher plants, cereals, and fungi (Basidiomycota)—with specialized focus on β-glucans. Key interests include carbohydrate chemistry, pharmacognosy, and the development of biopolymer-based pharmaceutical applications. Her work bridges fundamental structural characterization with practical drug delivery solutions, notably through liposome coating technologies and immunomodulatory compound development. Recent publications reveal a strong trajectory in fungal polysaccharide research, particularly with Pleurotus eryngii and Albatrellus ovinus species. Her team employs advanced techniques like diffusion-ordered NMR spectroscopy to analyze polysaccharide structures while investigating biological activities related to immune receptor binding (Dectin-1, Toll-like receptors) and therapeutic applications. This work demonstrates consistent output in high-impact journals including Carbohydrate Polymers and ACS Applied Bio Materials . She actively contributes to academic instruction through courses such as FARM1150 (Pharmaceutically Oriented Biochemistry), FARM3100 (Pharmacognosy), and FARM5200 (Use of Biopolymers in Pharmaceuticals). Her leadership extends to the Bioactive Natural Substances and Health Effects (BioNatH) research group and the Glyconor Consortium, where she investigates natural product applications for health improvement.

Jonathan Littleمشاهده پروفایل

استاد

• Exercise Physiology
• Metabolism
• Inflammation
• +۳ مورد دیگر

Jonathan Little is a Professor at the University of British Columbia Okanagan , affiliated with the Faculty of Health and Social Development and School of Health and Exercise Sciences . He leads the Exercise Metabolism and Inflammation Laboratory (EMIL) , focusing on the intersection of exercise physiology, nutrition, and metabolic disorders. Hons B. Kin – McMaster University, 2005 M.Sc. – University of Saskatchewan, 2007 Ph.D. – McMaster University, 2010 Postdoctoral Fellowship – UBC, 2010-2012 His research investigates how metabolic disruptions in type 2 diabetes affect cellular inflammation and how exercise/nutritional strategies can mitigate these effects. Key areas include high-intensity interval training (HIIT) , nutritional ketosis , and immunometabolic responses . EMIL combines human clinical trials with cellular/molecular experiments, utilizing advanced tools like flow cytometry and metabolic carts. His recent publications emphasize exercise snacks (short, frequent workouts), ketone supplements , and fasting protocols for managing diabetes and obesity. He has received prestigious awards like the Killam Accelerator Fellowship and CIHR New Investigator Award . Killam Accelerator Research Fellowship (2021-2023) Canadian Society for Exercise Physiology Young Investigator Award (2020) UBC Killam Research Fellowship (2018) Michael Smith Foundation for Health Research Scholar (2018-2023) American College of Sports Medicine New Investigator Award (2016) CIHR New Investigator Salary Award (2015-2020) He supervises graduate students in HMKN 313 – Exercise Metabolism and mentors through the HMKN 499 Research Practicum . His lab (EMIL) collaborates with institutions like the BC Diabetes Research Network and serves as an Associate Editor for Applied Physiology, Nutrition and Metabolism .

Praveen Bhugraمشاهده پروفایل

مدرس ارشد

• Cardiovascular Pharmacology
• Central Nervous System Pharmacology
• Autonomic Pharmacology
• +۲ مورد دیگر

Dr. Praveen Bhugra is a Senior Lecturer in Pharmacology at the University of Sunderland , where he has taught graduate courses including MPharm since 2006. His expertise spans cardiovascular, central nervous system, and autonomic pharmacology with a focus on receptor regulation in disease states. MSc (Pharmacology) from The Maharaja Sayajirao University of Baroda, India PhD (Medical Pharmacology) from Sardar Patel University, India His research integrates experimental pharmacology, molecular techniques (cell culture, calcium flux analysis), and biochemical approaches. Notably, he supervised PhD candidate Thomas Cherian (awarded 2014) on ureteral motility mechanisms. He authored the widely used textbook MCQs in Pharmacology (2000) and contributed to cardiovascular research during a 2000-2001 Visiting Scientist fellowship at the Institute of Cardiovascular Research, University of Manitoba, Canada. Recent publications (2015-2001) emphasize neurodegenerative pharmacology , hypertension mechanisms , and lipid mediator roles in cardiovascular disease . His work has been recognized with awards from the Indian Pharmacological Society and the International Society for Heart Research. Jaypur Prize (1985-86) C.L. Malhotra Research Prize (1994) Ahmedabad Branch Prizes (1996, 2001) National Academy of Medical Sciences Membership (2000) He has also contributed to public health research on probiotics in Clostridium difficile infection and participated in systematic reviews of substance abuse patterns in youth. Contact: praveen.bhugra@sunderland.ac.uk

Pierre Maechlerمشاهده پروفایل

استاد

• Mitochondrial metabolism
• Beta-cell function
• Diabetes research
• +۵ مورد دیگر

Pierre Maechler is a Professor at the University of Geneva's Faculty of Medicine in the Department of Cell Physiology and Metabolism. His research focuses on mitochondrial metabolism in pancreatic beta cells and its critical role in diabetes pathogenesis, with particular emphasis on glutamate dehydrogenase function and regulation. His laboratory investigates the molecular mechanisms of insulin secretion and beta-cell failure in Type 2 diabetes. Maechler's research interests span mitochondrial metabolism, energy homeostasis, and the molecular pathways linking nutrient sensing to insulin secretion. His work has established crucial connections between glutamate metabolism, beta-cell function, and diabetes development. He investigates how metabolic stressors like glucotoxicity and lipotoxicity impair beta-cell function through mitochondrial dysfunction. His research has expanded to include the role of glutamate dehydrogenase in multiple organs including brain, liver, and muscle, revealing systemic metabolic implications. Analysis of Maechler's publication record shows a sustained focus on beta-cell metabolism with evolving scope. Early work established fundamental mechanisms of glutamate signaling in insulin secretion, while recent publications demonstrate expansion into multi-organ metabolic regulation. His research has identified novel biomarkers for beta-cell mass, explored therapeutic targets for diabetes, and revealed unexpected roles for glutamate dehydrogenase in diverse physiological processes from muscle regeneration to brain function. The consistent thread through his work is understanding how mitochondrial metabolism governs cellular and systemic energy homeostasis. Professor Maechler has mentored numerous PhD students and postdoctoral fellows who have gone on to publish significant work in diabetes research. His laboratory collaborates extensively with clinical researchers to translate basic findings into potential therapeutic approaches for diabetes. Funding for his work likely comes from Swiss National Science Foundation and other European research agencies, supporting investigations into metabolic diseases. Maechler leads the Mitochondria and Energy Metabolism research group at the University of Geneva. His team employs a multidisciplinary approach combining molecular biology, metabolomics, and physiology to investigate metabolic regulation in health and disease. The laboratory maintains strong connections with clinical diabetes researchers, facilitating translational applications of their findings. Current work focuses on identifying novel therapeutic targets for preserving beta-cell function in diabetes.

Karl Peter Gieseمشاهده پروفایل

استاد

• Neurobiology of Mental Health
• Alzheimer's Disease
• Synaptic Plasticity
• +۶ مورد دیگر

Professor Karl Peter Giese holds the position of Professor of Neurobiology of Mental Health and Co-Head of the Basic & Clinical Neuroscience Department at King's College London's Institute of Psychiatry, Psychology & Neuroscience (IoPPN). His research focuses on memory mechanisms in health and disease, particularly Alzheimer's pathology, synaptic dysfunction, and aging effects. He leads projects funded by Alzheimer's Research UK and other institutions, investigating molecular and cellular bases of memory storage. His work bridges experimental models (e.g., mice) with translational insights for clinical applications. He has over 140 publications, including high-impact studies on CYFIP proteins in dementia and CaMKII in synaptic plasticity. Collaborations include researchers at King's College London and international partners. His lab explores mechanisms linking amyloid-beta, tau, and synaptic proteins to cognitive decline, with recent work applying computational methods to model aging brains. Education: PhD from ETH Zurich (1992), MSc Chemistry from Ruhr-University Bochum (1989). Current grants include Alzheimer's Research UK Network Centres and studies on MNK inhibition for Alzheimer's therapies. Projects span protein synthesis dysregulation, thalamic amyloid pathology, and intellectual disability genetics. His research has been featured in Nature Neuroscience , Brain , and Neuron . He advises on translational neuroscience initiatives and mentors early-career researchers.

Ben Allenمشاهده پروفایل

دانشیار

• Hedgehog Signaling
• Developmental Biology
• Signal Transduction Pathways
• +۳ مورد دیگر

Ben Allen is an Associate Professor in the Department of Cell and Developmental Biology at the University of Michigan. His research focuses on the mechanisms of growth factor and morphogen signaling, particularly Hedgehog (HH) signaling in development, tissue homeostasis, and cancer. Employing techniques such as mouse genetics, chicken in ovo electroporations, and biochemical analyses, his lab investigates HH signaling regulation in embryonic/postnatal development and diseases like pancreatic cancer. Recent work explores HH pathway roles in taste organ repair, kidney morphogenesis, and immunosuppressive tumor microenvironments. The lab's publications highlight interdisciplinary approaches, with keywords spanning developmental biology, cancer biology, and signal transduction. Subfields include pancreatic cancer progression, ciliary transport, GLI transcription factor dynamics, and tissue-specific signaling modulation. Collaborations with cancer researchers and regenerative medicine specialists are evident. Allen's group also contributes to science education initiatives, exemplified by their "Developing Future Biologists" program targeting underrepresented undergraduate students.

• Metabolic Signaling
• Pancreatic Islet Biology
• Signal Transduction Pathways
• +۴ مورد دیگر

Dr Amin Ardestani , Senior Lecturer in Metabolic Signaling at the Biomedical Institute for Multimorbidity (BIM), Hull York Medical School (HYMS) , specializes in unraveling molecular mechanisms of pancreatic β-cell failure in diabetes. His research program identifies novel therapeutic targets through signal transduction studies in metabolic disorders. Bachelor's in Biology, Tarbiat Moalem University (2004) Master's in Biochemistry, Institute of Biochemistry and Biophysics (2007) PhD in Biology, University of Bremen (2013) Junior Group Leader at University of Bremen (2014-2023) Research focuses on Hippo and mTOR signaling pathways in β-cell biology, autoimmunity, and regeneration. His work bridges mechanistic biology with drug discovery for diabetes, with significant findings on PHLPP1/2 phosphatases and MST1/2 kinases. Recent publications highlight therapeutic strategies for β-cell protection , including small molecule inhibitors (e.g., MST1/2 inhibitors) and metabolic enzyme modulation (LDHA). Collaborative studies explore SARS-CoV-2 interactions with pancreatic cells and cross-talk between acinar and β-cells in diabetes. 2019 JDRF Advanced Postdoctoral Fellowship 2018 Impulse grant & Career Advancement Award 2017 Early Investigators awards (Endocrine Society, EFSD/Lilly Programme) 2014 Albert Renold Fellowship & Bremer Studienpreis Professional roles include Editorial Board Member at Scientific Reports and Associate Editor at Frontiers in Endocrinology . He reviews grants for DFG, Diabetes UK, and ISF, and evaluates manuscripts for top-tier journals like Cell Metabolism and Nature Communications.

Roderick Limمشاهده پروفایل

دانشیار

• Nuclear Pore Complex Transport
• Mechanobiology of Cells and Tissues
• Biomimetic Molecular Transport Systems
• +۵ مورد دیگر

Prof. Dr. Roderick Lim is an Associate Professor at the Biozentrum, University of Basel , where he leads a research group since 2014. His work bridges biophysics, nanotechnology, and molecular biology , focusing on the nuclear pore complex (NPC) and mechanobiology of cells . He develops biomimetic systems for selective molecular transport and ARTIDIS , a nanomechanical tissue diagnostic platform commercialized for breast cancer prognosis . Education : BSc (UNC Chapel Hill), PhD (NUS/IMRE Singapore), Postdoc (Swiss Nanoscience Institute) Positions : Argovia Professor (2014–present), Tenure Track Asst. Prof. (2009–2013), Postdoc (2004–2008) His research on NPC transport selectivity reveals how karyopherins modulate the FG Nup barrier via multivalent interactions, with implications for viral entry and Alzheimer’s disease . His ARTIDIS platform uses atomic force microscopy to detect cancer via tissue softness, linking hypoxia to metastasis . Recent 2025 publications explore bacterial nanoharpoon defense mechanisms and DNA origami-based NPC mimics . Scientific Awards : Pierre-Gilles de Gennes Prize (2008), A*STAR Fellowship (2004) Collaborations : NCCR Molecular Systems Engineering, NanoTera, KTI He mentors PhD students in institutions across Switzerland, Singapore, Sweden, and the UK , with alumni working on polymersome delivery, mechanotransduction, and pathogen transport . His lab pioneered high-speed atomic force microscopy for real-time NPC dynamics and plasmonic nanopores for synthetic biology applications.