جست‌وجوی استاد و پژوهشگر

Harris H. Wangمشاهده پروفایل

دانشیار

• Systems Biology
• Synthetic Biology
• Genome Engineering
• +۱۷ مورد دیگر

Harris H. Wang is an Associate Professor in the Department of Systems Biology and Department of Pathology and Cell Biology at Columbia University's Vagelos College of Physicians and Surgeons, where he also serves as Interim Chair of Systems Biology. He is affiliated with the Center for Computational Biology and Bioinformatics (C2B2) and the Integrated Program in Cellular, Molecular and Biomedical Studies (CMBS). B.S., Physics and Mathematics, MIT Ph.D., Biophysics, Harvard University Dr. Wang's research lies at the intersection of systems and synthetic biology, focusing on developing foundational technologies for genome engineering, microbiome manipulation, and synthetic genomics. His lab pioneers methods such as MAGE, MAGIC, CAST, and CAMII to enable high-throughput genetic manipulation, in situ microbiome engineering, and AI-driven microbial culturomics. Key research themes include understanding microbial community dynamics, engineering cellular memory systems, designing biocontained genetic circuits, and applying synthetic biology to human health challenges in personalized medicine and infectious disease. His recent publications reveal a strong trend in spatial and functional metagenomics, CRISPR-based microbiome editing, and synthetic biology tools for data storage and genetic stability. The articles span high-impact journals like Nature , Science , and Nature Biotechnology , reflecting his leadership in developing scalable, programmable biological systems. Scientific Awards: NIH Director’s Early Independence Award Forbes 30 Under 30 in Science Sloan Research Fellowship NSF CAREER Award ONR Young Investigator Award Burroughs Wellcome Fund PATH Award Schaefer Scholar Blavatnik National Award Vilcek Prize PECASE Dr. Wang has advised numerous PhD and postdoctoral researchers, many of whom have gone on to independent scientific careers. His lab is supported by major grants from NIH, NSF, DARPA, DOE, and foundations including the Bill & Melinda Gates Foundation and CZ Biohub NY. He is actively involved in educational initiatives, including organizing Columbia’s iGEM team and the Cold Spring Harbor Laboratory Synthetic Biology course. The Wang Lab is based at the Columbia University Irving Medical Center and is part of national consortia such as the Engineering Biology Research Consortium (EBRC) and the Genome Project-Write (GP-Write) initiative. The lab develops and applies cutting-edge technologies in automation, machine learning, and synthetic biology to engineer microbiomes for applications in medicine, global health, and climate change.

• Microbiology
• Immunology
• Bacterial Vaccines
• +۵ مورد دیگر

James B. Kaper is a Professor and Chair of the Department of Microbiology & Immunology at the University of Maryland School of Medicine. He serves as Vice Dean for Academic Affairs and previously held leadership roles as Senior Associate Dean (2014–2019) and Chair (2007–present). His research focuses on the molecular pathogenesis of diarrheagenic Escherichia coli and Vibrio cholerae , including vaccine development and bacterial-host interactions. Education: BS (1973) and PhD (1979) in Microbiology from University of Maryland; Postdoc in Molecular Pathogenesis at University of Washington (1979–1981) Dr. Kaper’s work has led to the creation of live attenuated cholera vaccines, including CVD 103-HgR, the first licensed recombinant bacterial vaccine. His lab investigates bacterial genetics, intestinal colonization, and immune system activation, particularly TLR5 response to V. cholerae flagellin. He has authored 303 peer-reviewed articles and 68 book chapters. His research has been funded continuously by NIAID since 1982. Key publications include foundational work on V. cholerae vaccines (1984), genomic structure (1998), and quorum sensing in EHEC/EPEC (1999). His lab’s recent studies focus on phosphotyrosine proteomics (2013) and pathogenicity island regulation (2007). Scientific awards: Fellow, American Academy of Microbiology (1994); NIH Merit Award (2004); ASM DC White Award (2019) Editorial roles: Editor-in-Chief, EcoSal (2006–present); Associate Editor, International Journal of Medical Microbiology (2000–present) As an academic leader, Dr. Kaper has mentored over 60 graduate students and postdoctoral fellows. He holds multiple patents for cholera vaccines and E. coli diagnostics, including U.S. Patents 4,935,364; 5,399,494; and 6,204,004. His lab at UMSOM combines basic science with translational applications for enteric disease prevention.

• Evolutionary Biology
• Marine Biology
• Taxonomy
• +۵ مورد دیگر

Mikael Thollesson is a Senior Lecturer at Uppsala University, affiliated with the Department of Organismal Biology; Systematic Biology and Klubban’s Biological Station. His research focuses on evolutionary biology, phylogenetics, taxonomy, and molecular biology, particularly in marine and freshwater sponges (Porifera), bacterial pathogens, and computational methods in evolutionary analysis. Evolutionary Biology Marine Biology Taxonomy His recent publications highlight trends in sponge biodiversity, phylogeography, bacterial horizontal gene transfer, and mitochondrial gene evolution. Key articles include studies on Swedish demosponge faunas, Silene sect. Arenosae systematics, and computational tools like SPRIT for detecting gene transfers. No explicit awards or grants are mentioned.

Mihai Popمشاهده پروفایل

استاد

• Bioinformatics
• Genomics
• Computational Biology
• +۳ مورد دیگر

Dr. Mihai Pop is a Professor of Computer Science and Director of the University of Maryland Institute for Advanced Computer Studies (UMIACS). He holds appointments in the Department of Computer Science, UMIACS, and the Center for Bioinformatics and Computational Biology (CBCB). His research focuses on computational biology, metagenomics, and algorithm development for genomic data analysis. He received a Ph.D. in Computer Science from Johns Hopkins University (2000), followed by work at The Institute for Genomic Research (TIGR) developing genome assembly algorithms. Education: Ph.D., Computer Science, Johns Hopkins University, 2000. Research Interests: Bioinformatics, genomics, metagenomics, computational geometry, software testing. His lab develops tools for analyzing microbial communities and has pioneered methods for metagenomic assembly and analysis. Notable tools include the AMOS genome assembly toolkit. Recent Article Trends: Recent work emphasizes long-read sequencing, metagenomic profiling (e.g., TIPP3), and strain-level analysis (e.g., Strainy). He addresses challenges in scaling sequence-based searches and improving taxonomic resolution in large datasets. Awards: ACM Fellow (2019), ISCB Fellow (2022), UMD Excellence in Teaching Award (2015). Grants & Leadership: Co-leader of the Human Microbiome Project data analysis group. Active in diversity initiatives to promote inclusivity in computational fields. Labs/Teams: Pop Lab (pop-lab.org) focuses on computational methods for microbial genomics and metagenomics.

Matthias Mannمشاهده پروفایل

استاد

• Mass Spectrometry
• Proteomics
• Systems Biology
• +۶ مورد دیگر

Professor Matthias Mann is a world-leading scientist serving as Director of the Proteomics and Signal Transduction department at the Max Planck Institute of Biochemistry in Martinsried, Germany, and Director of the Proteomics department at the Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Denmark. With an h-index exceeding 277 and over 350,000 citations, he is recognized as the highest cited German researcher and one of the most influential scientists globally in proteomics. His educational background includes: Ph.D. in Chemical Engineering from Yale University (1988) Master's Degree in Physics from Georg August University Göttingen (1984) Bachelor's of Arts in Mathematics from Georg August University Göttingen (1982) Professor Mann's research focuses on advancing mass spectrometry-based proteomics to understand biological systems at the protein level. His work spans technological developments in mass spectrometry, bioinformatics and computational analysis, signal transduction and posttranslational modifications, and clinical proteomics applications for disease diagnosis and treatment. The Mann lab has pioneered groundbreaking methods like SILAC for quantitative proteomics and MaxQuant for proteome data analysis. Their vision is to translate proteomics knowledge into clinical practice for predictive, diagnostic, and preventive medicine, with recent work focusing on AI-guided platforms for analyzing proteomes from minimal tissue samples. Analysis of Professor Mann's recent publications reveals a strong trend toward clinical applications of proteomics, particularly in cancer research, metabolic diseases, and neurodegenerative disorders. His work increasingly integrates spatial proteomics, single-cell resolution techniques, and artificial intelligence approaches to uncover disease mechanisms and identify potential biomarkers, with a clear shift from basic technology development toward direct clinical applications and personalized medicine. Professor Mann has received numerous prestigious awards throughout his career: 2025: Elected member of the American National Academy of Sciences 2024: Dr. H.P. Heineken Award for Biochemistry and Biophysics 2023: Otto Warburg Medal 2019: Nominated member of the Bavarian Academy of Sciences 2013: Elected member of Leopoldina German National Academy of Sciences 2012: Körber European Science Award, Louis-Jeantet Foundation Prize for Medicine, Ernst Schering Prize, and Leibniz Prize Professor Mann leads a highly collaborative research team involved in multiple international networks including the Bill & Melinda Gates Foundation, Michael J. Fox Foundation for Parkinson's Research, CLINSPECT-M, and Munich Heart Alliance. His lab has mentored numerous successful researchers, with several former postdocs receiving prestigious ERC Starting Grants. The Mann group has developed innovative clinical proteomics pipelines for analyzing archived tissue specimens and body fluids, aiming to identify protein markers for early detection of diseases such as diabetes and cancer. The Mann lab operates across two major research centers with state-of-the-art mass spectrometry facilities. Their Clinical Knowledge Graph platform integrates multi-omics data with extensive metadata, creating an ecosystem for machine learning applications in proteomics. Current research focuses on developing highly sensitive methods that can profile thousands of proteins from minimal cell samples, enabling the identification of critical disease-related proteins and supporting the development of individualized therapies.

Knut Drescherمشاهده پروفایل

دانشیار

• Bacterial Biofilms
• Microbial Multicellularity
• Biophysics
• +۵ مورد دیگر

Prof. Knut Drescher is an Associate Professor at the Biozentrum, University of Basel , leading a research group focused on bacterial biofilms , swarming , and microbial multicellularity . Previously, he served as a Professor of Biophysics and Max Planck Research Group Leader at Philipps-Universität Marburg (2015-2021) and conducted postdoctoral research at Princeton University. Research Interests: Physical and biological mechanisms of biofilm formation Cell-cell interactions in microbial communities Antibiotic resistance in biofilms Hydrodynamics of bacterial swarms Evolution of cooperation in multispecies biofilms Development of bioimaging software (BiofilmQ, BacStalk) Scientific Awards: 2023: SNSF Consolidator Grant 2019: Heinz Maier-Leibnitz Prize (DFG), VAAM Research Prize, IUPAP Young Scientist Prize 2016: ERC Starting Grant Advising & Grants: Advises PhD and Master's students in microbiology, biophysics, and bioinformatics Secured major grants from ERC , HFSP , and DFG

Urs Jenalمشاهده پروفایل

استاد

• Bacterial Signal Transduction
• Microbiology
• Antibiotic Resistance
• +۵ مورد دیگر

Professor Urs Jenal is a Full Professor at the Biozentrum of the University of Basel, Switzerland, where he has led research on bacterial signal transduction since 2008. His laboratory investigates the molecular mechanisms of bacterial persistence and antibiotic resistance, with particular focus on pathogens causing chronic infections in humans. Previously, he served as Associate Professor (2002-2008) and Assistant Professor (1996-2002) at the same institution, and completed postdoctoral training at Stanford University and ETH Zurich. Education 2000: Habilitation and VENIA DOCENDI in Microbiology, University of Basel 1987-1991: PhD in Molecular Microbiology, ETH Zurich (supervisor: Prof. T. Leisinger) 1982-1986: Studies of Experimental Biology, ETH Zurich 1977-1981: Gymnasium with Matura Type C, Chur Research Focus Prof. Jenal's research centers on understanding how bacterial pathogens persist in the human body despite antibiotic treatments. His laboratory investigates cyclic nucleotides, particularly c-di-GMP, as signaling molecules that control bacterial biofilm formation, virulence, and antibiotic tolerance. His team studies pathogenic Escherichia coli causing recurrent urinary tract infections and Pseudomonas aeruginosa causing long-term lung infections in cystic fibrosis patients. Recent work has revealed how "sleeping" bacteria survive antibiotic treatments and how pathogens breach respiratory epithelia through goblet cell invasion. Scientific Recognition 2014: Elected member of the European Academy of Microbiology (EAM) 2013: ERC Advanced Investigator Award 2012: Elected member of the European Molecular Biology Organization (EMBO) 2011: Elected member of the American Academy of Microbiology (AAM) Mentorship and Collaborations Prof. Jenal has mentored numerous PhD students and postdocs, many receiving awards for their research. His laboratory is part of the NCCR AntiResist initiative focused on developing novel approaches against antibiotic resistance. He collaborates extensively with clinical researchers and has developed innovative models, including human mini-lungs, to investigate pathogen-host interactions. His recent publications demonstrate how understanding bacterial persistence mechanisms can lead to new therapeutic strategies against chronic infections.

• Pathogen Ecology
• Microbial Evolution
• Antibiotic Resistance
• +۴ مورد دیگر

Prof. Dr. Alex Hall is an Associate Professor at the Department of Environmental Systems Science and Head of the Institute of Integrative Biology at ETH Zürich , Switzerland. He holds a PhD from the University of Edinburgh (2008), followed by postdoctoral work at the University of Oxford and ETH Zürich, including prestigious SNSF Ambizione and Marie Curie Intra-European fellowships. Research Focus: The Hall lab investigates Microbial interactions in human microbiomes Antibiotic resistance evolution Horizontal gene transfer dynamics Computational and in vitro modeling of microbial communities Evolutionary medicine applications Scientific Contributions: His recent studies analyze probiotic treatments for Staphylococcus aureus decolonization, strain-specific ecological success in gut microbiomes, and CRISPR-Cas system roles in plasmid conflicts. The lab employs computational frameworks combined with experimental validations. Scientific Awards: SNSF Ambizione fellowship Marie Curie Intra-European fellowship He also serves on the SNSF PRIMA fellowship evaluation panel and the ETH Zürich Coordination Council Medicine .

Jennifer L Clarkeمشاهده پروفایل

استاد

• Statistical Methodology
• Bioinformatics/Computational Biology
• Data Mining/Machine Learning
• +۳ مورد دیگر

Jennifer L. Clarke is a Professor in the Department of Statistics at the University of Nebraska–Lincoln and Director of the Quantitative Life Science Initiative. She holds leadership roles in enabling big data integration across the University of Nebraska system through collaborative research programs. Her affiliations include the Institute of Agriculture and Natural Resources (IANR) and the College of Agriculture and Natural Resources. Dr. Clarke's research focuses on statistical methodology for high-dimensional data, computational biology, bioinformatics, and bacterial genomics. Her work bridges statistical innovation with applications in oncology, microbiome analysis, and agricultural phenomics. Key areas include predictive modeling, machine learning, and genomic/metagenomic data integration. Her recent publications span cancer biomarker discovery, plant phenotyping methodologies, and microbial community analysis, reflecting her interdisciplinary approach. Articles emphasize translational applications like therapeutic target identification and precision agriculture. Dr. Clarke leads initiatives fostering collaboration between statisticians and domain scientists, including the Quantitative Life Science Initiative and contributions to the Agricultural Genome-to-Phenome Initiative (AG2PI). Her work advances data-driven solutions for healthcare and food security challenges. Notable projects include developing statistical tools for microbiome studies, analyzing root architecture via 3D imaging, and investigating cranberry-derived compounds' cancer-inhibitory mechanisms. Her methodological contributions include hybrid clustering techniques and predictive model validation frameworks.

• Parasitology
• Molecular Biology
• Phylogenetics
• +۵ مورد دیگر

David Blair is a Professor at James Cook University, specializing in parasitic flatworms, molecular systematics, and evolutionary biology. His research focuses on understanding the genetic diversity, phylogeography, and host-parasite interactions of species such as Schistosoma, Paragonimus, and Opisthorchis. He has contributed extensively to studies on the molecular evolution of parasitic organisms and their implications for human and wildlife health. Key research areas include: molecular taxonomy of trematodes, phylogenetic analysis of parasitic flatworms, and genomic studies of host-parasite coevolution. Collaborations span global institutions, addressing public health challenges like paragonimiasis and fasciolosis. His work integrates field studies, lab-based molecular techniques, and computational biology to unravel evolutionary dynamics and ecological adaptations. Recent studies focus on the genetic diversity of Daphnia species, dugong population genetics, and drug-resistant Mycobacterium tuberculosis. His publications in journals like *Parasitology*, *Molecular Phylogenetics and Evolution*, and *Scientific Reports* highlight interdisciplinary approaches to parasitology and conservation biology.

Lawrence Goodridgeمشاهده پروفایل

استاد

• Food Safety
• Antibiotic Resistance
• Foodborne Pathogens
• +۶ مورد دیگر

Lawrence Goodridge is a Professor and Director of the Canadian Research Institute for Food Safety (CRIFS) at the University of Guelph's Ontario Agricultural College. He holds the Leung Family Professorship in Food Safety and leads research at the intersection of food safety, antibiotic resistance, and One Health principles. His work focuses on applying genomic technologies to study foodborne pathogens (E. coli, Salmonella, Listeria, Cronobacter) and leveraging wastewater surveillance for infectious disease outbreak prediction. Academic History: BSc Microbiology (University of Guelph, 1995), MSc Food Microbiology (2003), PhD Food Microbiology (2002), followed by post-doctoral training in Food Safety at the University of Georgia (2002). Joined CRIFS in 2003. Research Interests: Genomic analysis of pathogen emergence, wastewater-based epidemiology, bacteriophage applications, and consumer education strategies for food safety. His lab develops innovative methods for rapid pathogen detection in food systems and environmental samples. Articles Trends: Over 100 peer-reviewed publications emphasize genomic surveillance of foodborne pathogens and SARS-CoV-2, with a focus on wastewater sampling innovations. Recent work explores multi-modal data integration for public health forecasting and ethical data protection frameworks for surveillance programs. Awards: While no specific prizes are listed, his $50M+ research funding from Canadian/international sources underscores recognition of his impactful work. Grants support projects like phage-based sanitization and antimicrobial resistance tracking. Advising & Labs: Leads CRIFS laboratory operations and collaborates globally on food safety initiatives. His research has informed food industry guidelines and policy frameworks for mitigating pathogen risks in agricultural and environmental systems.

Joel Weadgeمشاهده پروفایل

دانشیار

• Bacterial Biofilms
• Bacterial Carbohydrates
• Protein Structure and Function
• +۷ مورد دیگر

Joel Weadge is an Associate Professor in the Biology Department at Wilfrid Laurier University , Waterloo, Ontario. His research focuses on bacterial biofilms, glycobiology, and protein structure-function relationships. Contact: jweadge@wlu.ca , Office: BA425 (Bricker Academic). Education: PhD in Microbiology (University of Guelph, 2006) BSc (Hons) in Microbiology (University of Guelph, 2000) Research Interests center on bacterial biofilms as virulence factors in pathogens like E. coli and Salmonella . Key areas include: Structural and functional characterization of biofilm proteins (cellulose, curli fimbriae) Enzymology of carbohydrate modifications (acetylation, phosphoethanolamine transfer) Developing therapeutics targeting biofilm synthesis Biopolymer applications for medical/industrial use Publications highlight studies on Pseudomonas and Salmonella biofilm mechanisms, glycosyltransferases, and carbohydrate-active enzymes, with methodologies spanning X-ray crystallography to high-throughput biofilm profiling. Labs and Teams: The Weadge Lab investigates biofilm roles in food/water security and oral health, utilizing enzymology, mass spectrometry, and structural biology. Current members include graduate students, technicians, and research assistants.

Jonathan Conwayمشاهده پروفایل

استادیار

• Plant-microbe interactions
• Biomolecular engineering
• Systems biology
• +۴ مورد دیگر

Jonathan Conway is an Assistant Professor in the Department of Chemical and Biological Engineering at Princeton University and an associated faculty member of the High Meadows Environmental Institute (HMEI). He leads the Conway Lab, which focuses on engineering plant-microbe interactions for applications in bioagriculture, bioenergy, and biochemical industries. Education: B.S. Chemical Engineering, University of Notre Dame (2011) M.S. Chemical Engineering, North Carolina State University (2013) Ph.D. Chemical Engineering, North Carolina State University (2017) Postdoctoral Fellow, University of North Carolina Chapel Hill & Howard Hughes Medical Institute (2017-2021) Research Interests: The Conway Lab develops genetic engineering approaches for non-model bacteria at plant-microbe interfaces. Key research areas include: chemical signaling between plants and microbes, microbiome impacts on plant immunity, environmental stress responses in agricultural systems, and enzymatic degradation of lignocellulosic biomass using thermophilic bacteria. The lab employs bacterial genetics, systems biology, and biomolecular engineering to create technologies for sustainable bioindustries. Publication Trends: Recent work demonstrates strong emphasis on molecular mechanisms of plant-microbe communication (2020-2024), enzyme characterization in biomass degradation (2024-2025), and development of synthetic microbial communities for climate resilience (2024). Earlier research focused on extremophile enzymology and metabolic engineering (2012-2019). Student Advising: Currently mentors 4 graduate students and 8 undergraduates. Alumni include 9 former advisees who graduated between 2022-2024. The lab actively recruits students through Princeton's Chemical Engineering graduate program and undergraduate research initiatives. Laboratory: The Conway Lab develops microfluidic systems for root microbiome studies and genetic tools for engineering plant-associated bacteria. Current projects include designing thermophilic microbial consortia for consolidated bioprocessing and characterizing bacterial immune evasion strategies.

Michael Baymمشاهده پروفایل

دانشیار

• Microbial Evolutionary Genomics
• Antibiotic Resistance
• Computational Biology
• +۷ مورد دیگر

Dr. Michael Baym is an Associate Professor of Biomedical Informatics at Harvard Medical School with affiliate appointments in Microbiology and the Laboratory of Systems Pharmacology, and as an Associate Member of the Broad Institute. He leads the Baym Lab, which studies microbial evolutionary genomics and antibiotic resistance through a hybrid of experimental, computational, and theoretical approaches. His research focuses on: Antibiotic Resistance Evolution and practical interventions Mobile Genetic Elements (plasmids, phages, transposons) Computational Genomic Algorithms for big data analysis Synthetic Biology tools and technologies Key recent publications explore phage discovery systems , phylogenetic compression of microbial genomes, and RNA-guided gene drives in plasmids. His work is supported by multiple NIH/NIGMS and NSF grants including a MIRA award. Scientific honors include: Packard Fellowship (2018) Pew Biomedical Scholarship (2020) Sloan Research Fellowship (2020) A. Clifford Barger Excellence in Mentoring Award (2021) SSQBio Mentorship Award (2022) The lab actively trains PhD students and postdoctoral fellows with alumni occupying academic and industry positions globally. Current team members include researchers from interdisciplinary backgrounds working at the intersection of experiment, computation, and theory .

Pamela D. Robertsمشاهده پروفایل

استاد

• Sustainable Disease Management
• Plant Pathology
• Integrated Pest Management
• +۳ مورد دیگر

Dr. Pamela D. Roberts is a Professor of Plant Pathology and State Extension Specialist for Vegetable Pathology at the University of Florida's Southwest Florida Research and Education Center (SWFREC) in Immokalee, FL. She holds a B.Sc. in Horticultural Sciences from Kansas State University, an M.S. in Plant Pathology from the University of Hawaii, and a Ph.D. in Plant Pathology from the University of Florida. Her research focuses on sustainable disease management in vegetables and specialty crops, emphasizing integrated management strategies for bacterial and fungal-like pathogens. She leads the Florida Extension Plant Disease Diagnostic Laboratory at SWFREC, offering diagnostic services and disease management recommendations. Her extension programs include educational outreach on plant diseases and field demonstrations of integrated management techniques. Dr. Roberts has received prestigious awards such as the UF/IFAS Jim App Team Award and the Dallas Townsend Distinguished Extension Award. She serves as Editor-in-Chief of the American Phytopathological Society journal Plant Health Progress . Her work spans disease diagnosis, epidemiology, and pathogen evolution, with a strong emphasis on crops like tomato, pepper, and citrus. Her research publications address topics such as Xanthomonas pathogen diversity, remote sensing for disease detection, and sustainable agricultural practices. She collaborates on projects involving molecular diagnostics, pest management strategies, and crop resilience. Ongoing efforts include combating bacterial spot diseases, whitefly-transmitted viruses, and citrus black spot.