جست‌وجوی استاد و پژوهشگر

Morgan Herodمشاهده پروفایل

پژوهشگر ارشد

• RNA viruses
• Virus Replication
• Virion Morphology
• +۱۲ مورد دیگر

Dr Morgan Herod is an MRC CDA Fellow and University Academic Fellow in the School of Molecular and Cellular Biology at the University of Leeds, Faculty of Biological Sciences. His research focuses on the molecular mechanisms of RNA virus replication, particularly in clinically relevant viruses such as norovirus and hepatitis E virus. He leads an active research group employing interdisciplinary approaches that integrate molecular virology, structural biology, genetics, and classical virology. The Herod lab investigates key stages in the viral life cycle, including capsid disassembly and cellular entry, viral polyprotein processing, genome replication, and virion assembly. A major focus is understanding how norovirus capsids interact with host molecules to regulate entry and infectivity, using techniques such as structural imaging and biomolecular interaction assays. Another core project explores the molecular composition of viral replication complexes in norovirus and picornaviruses, aiming to elucidate how newly synthesized genomes are packaged into new virions. Additionally, his work on hepatitis E virus examines how polyprotein processing regulates RNA replication and the functional roles of non-structural proteins within the replication complex. Dr Herod holds a prestigious Medical Research Council (MRC) Career Development Award, supporting his work on fundamental virological mechanisms with implications for disease control. His research aims to translate mechanistic insights into novel antiviral strategies targeting gastrointestinal viral infections. Research focus on RNA viruses impacting human and animal health Interdisciplinary approach combining structural, molecular, and cellular techniques Host institution: University of Leeds, a leading UK research university Scientific Awards: MRC Career Development Award (CDA) Fellow Dr Herod's work is supported by competitive fellowship funding, indicating recognition of his research potential and contributions to virology. While no formal advisees are listed in the provided text, he likely supervises postgraduate researchers within his lab, given the presence of an established research program. His lab is part of the Astbury Centre for Structural Molecular Biology at Leeds, as suggested by the associated image URLs, indicating collaboration within a major structural biology hub.

David M. Geiserمشاهده پروفایل

استاد

• Molecular Evolutionary Genetics
• Fungal Systematics
• Phylogenetics
• +۷ مورد دیگر

David M. Geiser is a Professor in the Department of Plant Pathology and Environmental Microbiology at Pennsylvania State University, where he conducts research in molecular evolutionary genetics and systematics of fungi. His work focuses on the phylogenetics and taxonomy of Fusarium and related plant pathogens, with implications for agriculture and food safety. His research interests include molecular phylogenetics, species complex delineation, DNA sequencing, fungal genomics, and mycotoxin production. He is a leading expert in the taxonomy and identification of Fusarium , contributing to major resources such as FUSARIUM-ID. His work integrates genomic, phylogenetic, and morphological data to resolve fungal species boundaries and improve diagnostic accuracy. The recent publications show a strong trend in phylogenomics, fungal taxonomy, and molecular diagnostics, particularly within the Fusarium genus. His research spans species discovery, misidentification issues in culture collections, trichothecene potential, and the development of genomic tools for pathogen identification. These works reflect a deep engagement with both fundamental fungal systematics and applied plant pathology. Elected to leadership in the Mycological Society of America Dr. Geiser has supervised and collaborated with numerous researchers, including PhD students and postdoctoral scholars, though formal advisees are not explicitly listed. He has been involved in multiple collaborative grants focused on fungal genomics, taxonomy, and plant disease diagnostics. His laboratory is part of a broad network of fungal researchers and contributes to international efforts in fungal nomenclature and classification. His lab is involved in high-impact collaborative research, particularly in the areas of fungal phylogenomics and diagnostic tool development. He is part of a global consortium working on fungal taxonomy and sequence-based nomenclature, contributing to standards that shape modern mycology.

Gary Schindelmanمشاهده پروفایل

استاد

• Biochemistry
• Molecular Biology
• Genomics
• +۷ مورد دیگر

Gary Schindelman is a Professor of Biochemistry at Occidental College and a biological curator for WormBase at Caltech. He earned his B.S. from the State University of New York at Binghamton and his Ph.D. from New York University. Appointed in 2005, he also serves as a Department Co-Chair in Biochemistry. Email: schindelman@oxy.edu Office: Bioscience 208A Office Hours: Tuesday 9:45 – 11:45 a.m., Wednesday 1:00 – 2:00 p.m., and by appointment (Zoom or in person) Dr. Schindelman's research focuses on Biochemistry, Molecular Biology, Genomics , and Computational Biology , particularly in C. elegans and Arabidopsis models. His work spans enzyme kinetics, RNA biology, cellulose microfibril orientation, and bioinformatics tools for nematode research. He has contributed to WormBase, a key resource for nematode genomics, and explored ventral nerve cord functions in C. elegans behavior. His publications highlight expertise in genomic databases , phenotype ontologies , and plant cell expansion mechanisms . He received the Donald R. Loftsgordon Memorial Award for Outstanding Teaching in 2015. Dr. Schindelman teaches courses including Molecular Biology (BIO 221) , Principles of Biochemistry (BIO 322) , and Biochemistry I (BIO 349) , covering DNA/RNA/protein structure, enzyme function, intermediary metabolism, and biochemical techniques.

• Biochemistry
• RNA Structure
• Structural Biology
• +۶ مورد دیگر

Jessica Brown is an Associate Professor in the Department of Chemistry and Biochemistry at the University of Notre Dame, where she leads a research group focused on RNA structure and function. Her lab investigates the structural, biochemical, and cellular roles of RNA triple helices, with a particular emphasis on the MALAT1 triple helix and its implications in cancer biology. Education: Ph.D. in Biochemistry, The Ohio State University (2010) B.S. in Chemistry and Biological Sciences, Wright State University (2005) Her research lies at the intersection of biochemistry, structural biology, and molecular oncology. She explores fundamental questions about RNA triple helix formation, stability, protein interactions, and degradation pathways. Using techniques such as X-ray crystallography, cryo-EM, and high-throughput assays, her work aims to uncover the biophysical principles governing RNA triplexes and their regulatory roles in human disease. The recent publications from her lab highlight a strong trend in RNA modification, non-coding RNA structure, and therapeutic targeting of oncogenic RNAs. Her studies span from mechanistic enzymology (e.g., METTL16 kinetics) to disease-associated structural rearrangements in MALAT1, reflecting a multidisciplinary approach that bridges basic science and translational applications. Scientific Awards: NIH Pathway to Independence Award (K99/R00), 2014–2019 American Cancer Society Postdoctoral Fellowship, 2012–2014 OSU Presidential Fellowship, 2010 American Heart Association Predoctoral Fellowship, 2008–2010 Dr. Brown advises graduate students and postdoctoral researchers in her lab, fostering training in cutting-edge biochemical and structural methods. While specific grant details are not listed, her sustained research output and prestigious fellowships indicate active external funding. Her lab is positioned at the forefront of RNA structural biology, with future work likely to expand the understanding of the 'triplexome' and develop tools for targeting stable RNA structures in disease. Labs and Research Teams: The Brown Laboratory at the University of Notre Dame employs a collaborative, interdisciplinary team of researchers using structural, biochemical, and cellular approaches to study RNA triple helices. The lab actively recruits graduate and postdoctoral trainees and contributes to major discussions in RNA biology and epitranscriptomics.

Darshana M. Dadhaniaمشاهده پروفایل

دانشیار

• Transplantation Medicine
• Nephrology
• Kidney Transplantation
• +۱۰ مورد دیگر

Darshana M. Dadhania, M.D., M.S., D(ABHI), is an Associate Professor of Medicine at Weill Cornell Medical College and an Associate Attending Physician at NewYork-Presbyterian Hospital. She serves as Medical Director of the Kidney and Pancreas Transplant Program and Program Director of the Transplant Nephrology Fellowship. Additionally, she is Director of the Genomics Division and Associate Director of the Immunogenetics and Transplantation Center. Education: M.D. from University of Medicine and Dentistry of NJ; M.S. in Clinical and Translational Investigation from Weill Cornell; B.A., B.S. from Stevens Institute of Technology. Training: Internal Medicine Residency, Nephrology Fellowship, and Transplant Medicine Fellowship at NewYork-Presbyterian Hospital; additional training in histocompatibility testing. Certifications: Board Certified in Internal Medicine and Nephrology; Diplomate, American Board of Histocompatibility and Immunogenetics. Dr. Dadhania's research focuses on noninvasive biomarkers for kidney allograft outcomes, particularly urinary cell mRNA and cell-free DNA profiling for rejection detection, management of highly sensitized patients, and infectious complications post-transplant. She has pioneered work in gut microbiota interactions with immunosuppression and infection risk. Her studies integrate genomics, immunology, and clinical outcomes to improve long-term transplant success. Her recent publications (2023–2025) emphasize noninvasive diagnostics using urinary biomarkers, consensus development in antibody-mediated rejection (Banff Working Group), kidney paired donation trends, and integration of palliative care in transplant failure. These works span high-impact journals including Nature Medicine , American Journal of Transplantation , and Transplantation , reflecting a strong translational and clinical research trajectory. Elected Fellow, American Society of Transplantation (2015) President, New York Society of Nephrology (2014–2015) Chair, Kidney Pancreas Community of Practice, American Society of Transplantation (2017–2019) Co-Chair, Consensus Conferences on Frailty, Cardiovascular Disease, and Heart-Kidney Transplantation Editorial Board, Nephrology, Dialysis and Transplantation and Transplantation Recipient of multiple investigator awards and leadership recognitions since 2003 Dr. Dadhania has served as site Principal Investigator for NIH-supported CTOT-03 and CTOT-04 trials and currently leads multiple studies including the APOLLO Consortium and metagenomic profiling of urinary cell-free DNA. She mentors fellows through her fellowship directorship and contributes to national policy via consensus guidelines and editorial leadership. Her work bridges clinical care, research innovation, and education in transplant nephrology. She leads the Genomics Division and Immunogenetics and Transplantation Center, where her team develops and validates molecular assays for allograft monitoring. Her lab collaborates extensively with biopharma partners and national consortia to translate biomarkers into clinical practice.

Thomas B Bartnikasمشاهده پروفایل

دانشیار

• Metal Homeostasis
• Iron Metabolism
• Manganese Metabolism
• +۳ مورد دیگر

Thomas B Bartnikas is an Associate Professor of Pathology and Laboratory Medicine at Brown University and Director of the MD/PhD Program. His research focuses on metal homeostasis in human biology, particularly iron and manganese regulation in health and disease. Education: PhD in Molecular Cell Biology (Washington University in St. Louis, 2004) MD (Washington University in St. Louis, 2004) BA (Cornell University, 1996) Dr. Bartnikas investigates molecular mechanisms of metal absorption, distribution, and elimination using mouse and cell culture models. His work connects genetic mutations, dietary imbalances, and environmental exposures to metal-related disorders like hemochromatosis. Recent publications emphasize hepcidin regulation, divalent metal transport, and metal toxicity pathways. Scientific contributions include: NIH-funded research on iron and manganese homeostasis Development of novel animal models for metal disorders Key discoveries in transferrin and BMP signaling interactions He received the NIDDK K99/R00 DK084122 award and collaborates with international BioIron researchers. Dr. Bartnikas teaches BIOL 2860 - Molecular Mechanisms of Disease and contributes to biomedical science education through the MD/PhD program.

Attila Kumanovicsمشاهده پروفایل

استاد بالینی

• Molecular genetic pathology
• Immunology
• Primary immunodeficiency diseases
• +۵ مورد دیگر

Attila Kumanovics, M.D., is a Clinical Professor in the Department of Laboratory Medicine and Pathology at Mayo Clinic in Rochester, Minnesota, USA. A board-certified clinical pathologist (American Board of Pathology, 2011) and molecular genetic pathologist (American Board of Pathology, 2012), he focuses on molecular and cellular immunology testing and the diagnosis of inborn errors of immunity. Education & Certifications Board Certification – Molecular Genetic Pathology, American Board of Pathology, 2012 Board Certification – Clinical Pathology, American Board of Pathology, 2011 M.D. (institution & year not specified in text) Research Focus Dr. Kumanovics’ research integrates cutting-edge molecular genetic techniques with clinical immunology to uncover the genetic underpinnings of primary immunodeficiency diseases. His work spans: Molecular Genetic Pathology: Development and validation of next-generation sequencing assays for HLA typing and immunodeficiency gene panels. Primary Immunodeficiencies: Identification and characterization of novel monogenic defects affecting immune cell development and function. Diagnostic Immunology: Optimization of flow-cytometric and functional assays for immune cell subset analysis and autoantibody detection. Publication Impact With 61 peer-reviewed publications from 1995 to 2025, Dr. Kumanovics has produced an influential body of work that advances both basic understanding and clinical practice. Landmark papers include the 2024 Science Advances study on ITPR3 variants, multi-author reviews on primary immunodeficiency diagnostic guidelines, and technical articles on next-generation HLA typing and flow cytometry. His research trajectory illustrates a steady evolution from foundational immunology and mouse models toward high-resolution genomic diagnostics and international consensus guidelines. Scientific Awards & Recognition Board Certification – Molecular Genetic Pathology, American Board of Pathology (2012) Board Certification – Clinical Pathology, American Board of Pathology (2011) Active contributor to American Academy of Allergy, Asthma & Immunology working groups Collaborations & Teams Dr. Kumanovics collaborates extensively within Mayo Clinic’s Department of Laboratory Medicine and Pathology, serving as a key resource for molecular genetic pathology consultations. He participates in multi-institutional consortia such as the Primary Immunodeficiency Diseases Committee of the American Academy of Allergy, Asthma & Immunology, co-authoring diagnostic frameworks that are used worldwide. Details of specific laboratories or grant funding were not disclosed in the provided text.

Thomas C. Richمشاهده پروفایل

استاد

• Cell Signaling
• cAMP Signaling
• Biomedical Imaging
• +۵ مورد دیگر

Thomas C. Rich serves as Professor of Pharmacology and Director of the Bioimaging Core Facility at the University of South Alabama's Frederick P. Whiddon College of Medicine, where he leads innovative research in cellular signaling dynamics and advanced imaging technologies. His educational background includes: Baccalaureate with Honors in Engineering from Georgia Institute of Technology Masters in Aerospace Engineering from Georgia Institute of Technology Ph.D. in Biomedical Engineering from Vanderbilt University Dr. Rich's research focuses on cellular signaling specificity , particularly cAMP pathways and phosphodiesterase regulation . His laboratory pioneered single-cell cAMP sensors and excitation-scanning hyperspectral imaging (HSI) techniques enabling 100-fold signal-to-noise improvements over traditional FRET. Key contributions include mapping cAMP gradients in pulmonary endothelial cells and airway smooth muscle, revealing previously undetectable signaling microdomains through collaborations with Dr. Silas Leavesley and Dr. Michael Francis. Analysis of his 14 publications (2015-2024) shows consistent innovation in quantitative imaging and signal transduction , with increasing emphasis on multi-parametric measurement (cAMP, Ca2+, NO, cGMP) and real-time dynamic tracking . His work spans fundamental enzymology to clinical applications, particularly in respiratory physiology and endoscopic technology development. No scientific awards were mentioned in the provided documentation. While specific advisees and grant details are not documented, Dr. Rich's research program demonstrates extensive collaboration through co-authorship patterns and facility leadership. His Bioimaging Core Facility serves as a hub for interdisciplinary projects requiring advanced fluorescence measurement capabilities. Dr. Rich leads the Bioimaging Core Facility in a collaborative research ecosystem centered around hyperspectral imaging development. His team works closely with Dr. Leavesley on optical system engineering and Dr. Francis on dynamic region-of-interest algorithms, creating an integrated approach to overcome limitations in cellular signal measurement within the 'turbulent maelstrom of the cellular environment'.

Gabriel Bosséمشاهده پروفایل

استادیار

• Neuroscience
• Opioid Addiction
• Neurosteroids
• +۷ مورد دیگر

Gabriel Bossé is an Assistant Professor at the Department of Psychiatry and Neuroscience , Faculty of Medicine, Laval University. His research focuses on leveraging zebrafish models to investigate the neurobiology of opioid addiction , neurosteroid effects on behavior , and long-term consequences of neonatal opioid exposure . He employs genetic tools (CRISPR-Cas9, transgenic lines), pharmacology, and imaging to uncover novel biological pathways and therapeutic targets for addiction. Key Techniques: Behavioral assays, molecular imaging, CRISPR-Cas9, miRNA analysis Laboratory: Boosé Lab , focusing on integrative neuroscience and experimental therapies His work bridges addiction biology and drug discovery , emphasizing neurosteroid pathways and genetic/pharmacological interventions . Publications highlight opioid self-administration mechanisms, neurosteroid modulation, and miRNA turnover in neuronal systems. For contact: gabriel.bosse@cervo.ulaval.ca . Lab website and academic profiles are accessible via Twitter , ORCID , and Google Scholar .

Melissa Gammonsمشاهده پروفایل

پژوهشگر

• Wnt signaling
• Signal transduction
• Rare genetic diseases
• +۳ مورد دیگر

Melissa Gammons is a Researcher at the University of Cambridge , affiliated with the Cambridge Institute for Medical Research (CIMR) and the Department of Medical Genetics . Her work focuses on molecular mechanisms of Wnt signaling in health and disease, with strategic themes including Membrane Trafficking, Organelle Biology, Rare Genetic Diseases, and Neurological Diseases. Her research explores how Wnt signaling pathways regulate cellular processes like proliferation, differentiation, and polarity. She investigates misregulation of these pathways in diseases such as Robinow Syndrome, aiming to inform targeted therapies for rare genetic disorders, cancer, and neurological conditions. Her work often intersects with VEGF signaling in angiogenesis and ocular disease models. Funding : Wellcome Trust, MRC-AstraZeneca Blue-Sky collaboration Group Members : Dr. Miha Renko, Elisabeth Chapman, Christina Antoniou, Anton Venhuizen Contact : mg2128@cam.ac.uk Recent publications highlight her contributions to understanding Wnt signalosome assembly, feedback loops, and VEGF splicing regulation. She actively supervises PhD students and collaborates with industry partners for drug discovery.

Bena Brownمشاهده پروفایل

عضو هیئت علمی

• Aboriginal and Torres Strait Islander health
• Oncology
• Cancer survivorship
• +۴ مورد دیگر

Dr Bena Brown is a clinician/researcher and Adjunct Senior Fellow at the UQ Poche Centre for Indigenous Health , affiliated with the Faculty of Health and Behavioural Sciences at the University of Queensland. She is also an Advanced Speech Pathologist at Brisbane's Princess Alexandra Hospital and supervises higher-degree students in the School of Health and Rehabilitation Sciences . Her work bridges clinical practice and research to enhance cancer care for Aboriginal and Torres Strait Islander peoples . Research Interests : Cancer Care, Survivorship, Novel Service Delivery Models, Telehealth, Patient-Centered Care. Grants : Over $3.6 million in research funding, including projects like Yarning About Cultural Safety and PROMISE . Committee Memberships : Human Research and Ethics Committees at Metro South Health, Queensland Collaborative for Cancer Survivorship, COSA Patient-Reported Outcome Working Group. Publications : Over 60 peer-reviewed articles focusing on head and neck cancer outcomes , lymphoedema , dysphagia , and culturally responsive care .

Rachelle Crosbieمشاهده پروفایل

استاد

• Duchenne muscular dystrophy
• Protein biochemistry
• Muscle physiology
• +۵ مورد دیگر

Rachelle Crosbie is a Professor and Department Chair at the University of California, Los Angeles (UCLA), specializing in Integrative Biology and Physiology. Her research focuses on Duchenne muscular dystrophy (DMD), sarcospan, and extracellular matrix interactions in muscle health and disease. She earned her B.S. in Biochemistry from Texas A&M University (1989) and her Ph.D. in Biochemistry from UCLA (1994). Postdoctoral work was conducted at the University of Iowa Carver College of Medicine, supported by the Muscular Dystrophy Association. Her lab investigates sarcospan's role in ameliorating dystrophic muscle by activating compensatory mechanisms. Research includes developing small molecule therapies, in vitro platforms for fibrosis studies, and multi-omics approaches to cytoskeletal remodeling. She leads an NIH T32 training grant for muscle research. Scientific awards include the UCLA Chancellor’s Distinguished Teaching Award, Coalition Duchenne Lotus Award, and National Academies Education Scholar recognition. She developed an online DMD course for UC campuses and contributed to education research on student engagement in asynchronous learning.

Rachel Tannerمشاهده پروفایل

دانشیار

• Tuberculosis vaccine research
• Immune correlates of protection
• Humoral immune response
• +۵ مورد دیگر

Rachel Tanner is an Associate Professor and Lecturer in Human Sciences at Wadham College, University of Oxford, with additional appointments as Research Fellow at Wolfson College and Access Officer for the Institute of Human Sciences. Her research focuses on tuberculosis vaccine development through analysis of immune correlates, particularly the humoral response to BCG vaccination and development of functional in vitro assays. Education MA in Biological Sciences, University of Oxford DPhil in Clinical Medicine, University of Oxford Her work addresses critical gaps in TB vaccine development by: Identifying humoral immune correlates of protection Developing in vitro mycobacterial growth inhibition assays (MGIA) to reduce animal use Investigating controlled human infection models Exploring non-specific effects of BCG vaccination Advancing bovine TB vaccine research She leads initiatives aligning with the 3Rs principles for animal research. Notable scientific awards include: TBVI Young Scientist Award (2017) CTVD Early Career Scientist Award (2018) 'Women of the Future' Award for Science (2019) Current research projects involve: Comparative analysis of BCG and MTBVAC vaccines Route-specific antibody functionality Development of novel TB vaccine candidates Standardisation of functional immune assays She contributes to scientific governance through roles on: British Society for Immunology Vaccine Affinity Group Acid Fast Club committee Oxford University Animal Care and Ethical Review 3Rs subcommittee Scientific Reports Editorial Board

• Infectious Diseases
• Veterinary Microbiology
• Antimicrobial Resistance
• +۷ مورد دیگر

Maurice Byukusenge is a Clinical Assistant Professor at the Animal Diagnostic Lab , Pennsylvania State University, affiliated with the Department of Veterinary and Biomedical Sciences . His research focuses on zoonotic pathogens, molecular diagnostics, and One Health approaches. Specializations: Infectious diseases, antimicrobial resistance, virology, and genomics. Affiliations: Center for Infectious Disease Dynamics, One Health Microbiome Center. Byukusenge's work spans molecular epidemiology of bacterial pathogens like Brucella , Salmonella , and Escherichia coli , with applications in veterinary diagnostics and public health. His publications highlight the use of genomic tools to track pathogens across species and regions. Key trends in his research include leveraging PCR techniques and whole-genome sequencing for pathogen detection, vaccine development, and understanding zoonotic disease transmission. Collaborative efforts with institutions in Tanzania, Rwanda, and the U.S. underscore his global One Health perspective. He contributes to the Animal Diagnostic Lab , advancing diagnostics for livestock and wildlife diseases. His work intersects with food safety, wildlife health, and antimicrobial resistance mitigation.

Seth Parkerمشاهده پروفایل

استادیار

• Cancer Metabolism
• Nutrient Transporter Biology
• Childhood Leukemia
• +۶ مورد دیگر

Dr. Seth Parker is an Assistant Professor in the Department of Biochemistry and Molecular Biology at the University of British Columbia Faculty of Medicine . Based at BC Children’s Hospital, his research group deciphers how nutrient transporters and metabolic reprogramming drive diseases such as cancer, with a special focus on childhood leukemia. He combines biochemical assays, molecular biology, and cutting-edge mass-spectrometry platforms to reveal druggable metabolic vulnerabilities. Research Interests Transporter Biology: Discovery and functional characterization of solute carrier (SLC) transporters that dictate nutrient flux in diseased cells. Compartmentalized Metabolism: Development of organelle-specific metabolomics to understand how enzyme isoform localization provides a proliferative advantage to tumors. Pediatric Leukemia: Identification of selective metabolic dependencies in relapsed childhood leukemia and evaluation of transporter-targeted therapies as alternatives to systemic nutrient depletion. Research Output & Trends Across 2020-2024, Dr. Parker has co-authored multiple high-impact studies ( Nature, Cell, Nat Cancer, Cancer Discov ) that collectively map metabolic rewiring in pancreatic cancer, glioma, Ewing sarcoma, and leukemia. A consistent theme is the integration of metabolomics, proteomics, and in vivo models to translate metabolic findings into therapeutic strategies. Scientific Awards No specific awards were listed in the provided text. Training & Mentorship Dr. Parker actively recruits graduate students, post-doctoral fellows, and research associates. His lab website invites prospective trainees to inquire about opportunities in metabolomics, transporter biology, and pediatric cancer research. Labs & Teams The Parker Laboratory is located in the BC Children’s Hospital Research Institute, with access to core facilities for mass spectrometry, flow cytometry, and animal models, fostering collaborative networks across UBC and the BC Cancer Research Centre.