Przemysław Zarębaمشاهده پروفایل
استادیار
Dr. Przemysław Zaręba is a Research and Teaching Assistant Professor at the Department of Chemical Technology and Environmental Analytics within the Faculty of Chemical Engineering and Technology at Tadeusz Kościuszko Cracow University of Technology. He holds a Doctor of Engineering degree (2023) and Master of Science in Engineering (2017), both from the same institution, specializing in Chemical Engineering and Light Organic Technology respectively. His research interests span cancer pharmacotherapy, central nervous system diseases, bioactive compound design, molecular modeling, and specifically focus on 5-HT receptor ligands and the PI3K/AKT/mTOR pathway for treating prostate cancer, glioblastoma, and other oncological conditions. Dr. Zaręba has developed expertise in designing dual-target inhibitors that simultaneously address multiple signaling pathways involved in cancer progression. Analysis of his recent publications reveals a strong focus on innovative therapeutic approaches targeting serotonin receptors (particularly 5-HT5A, 5-HT6, and 5-HT7) in various cancers, with emphasis on prostate cancer, glioblastoma, and triple-negative breast cancer. His work combines molecular modeling, organic synthesis using green chemistry principles, and comprehensive biological evaluation to develop novel therapeutic agents. Winner of the National Centre for Research and Development's LIDER program (14th edition, 2023) Recipient of the FNP Start scholarship (2023) Principal investigator for Proof of Concept grant (FNP, FENG perspective) Dr. Zaręba leads multiple significant research projects with substantial funding, including the LIDER14/0035/2023 project on 5-HT5A receptor ligands for castration-resistant prostate cancer (2024-2027), and collaborates with institutions like Nicolaus Copernicus University in Toruń on NCN Opus projects. His team includes researchers with complementary expertise in organic synthesis, pharmacological testing, and molecular modeling, creating a multidisciplinary approach to drug discovery.


