معرفی
Zoya Leonenko is a Professor and University Research Chair at the University of Waterloo, affiliated with the Department of Physics and Astronomy. Her research focuses on biophysical mechanisms of neurodegenerative diseases, particularly Alzheimer's, emphasizing lipid membrane interactions and amyloid-beta toxicity. She employs advanced techniques such as atomic force microscopy (AFM), Kelvin probe force microscopy (KPFM), and localized surface plasmon resonance (LSPR) to investigate molecular-scale phenomena.
Her work explores the role of melatonin, trehalose, and lithium isotopes in mitigating amyloid-induced membrane damage. Notable contributions include studies on mitochondrial ion transport, lipid nanodomain formation, and the quantum effects of lithium isotopes in neuronal activity. She leads the Leonenko Research Group, advancing interdisciplinary research at the interface of physics, chemistry, and neuroscience.
Research Highlights:
- Developed novel methods to quantify amyloid-membrane interactions using AFM and LSPR.
- Discovered lithium isotope effects on mitochondrial ion channels, suggesting quantum biology implications.
- Identified melatonin's role in stabilizing lipid membranes against amyloid toxicity.
Future Work: Expanding studies on neuroprotective agents, lipid membrane dynamics in disease, and quantum effects in neurobiology.
