معرفی
Zongling Ji is a Researcher at the Division of Molecular & Cellular Function within the Faculty of Biology, Medicine and Health at the University of Manchester. With qualifications including MB ChB, MSc, and PhD, Dr. Ji focuses on molecular mechanisms of gene regulation and their implications in disease processes.
Dr. Ji's research expertise spans several key areas of molecular biology and genetics:
- Transcription factor biology, particularly focusing on Forkhead transcription factors (FOXK2, FOXM1)
- Gene regulation mechanisms in stem cells and cancer
- Transposable element control and genomic stability
- Post-translational modifications affecting transcriptional regulation
Analysis of Dr. Ji's publication record reveals a consistent trajectory from fundamental mechanisms of gene regulation to disease applications. The research demonstrates expertise in how transcription factors premark genes for activation during cellular differentiation, how post-translational modifications affect transcription factor function in cancer cells, and how transcriptional networks become deregulated in cancers. This work bridges basic science with potential clinical applications in oncology.
Dr. Ji's research contributes to UN Sustainable Development Goals related to good health and well-being, reflecting the translational potential of this work. Publications in journals such as eLife, Nucleic Acids Research, and Molecular Cancer demonstrate the impact of this research within the scientific community.
As an active researcher, Dr. Ji collaborates extensively with colleagues at the University of Manchester and internationally, contributing to the global understanding of gene regulation mechanisms and their dysregulation in disease states.
