معرفی
Zhou Xing is a Professor of Medicine at McMaster University's Faculty of Health Sciences, with a distinguished career in immunology and vaccine research. His work focuses on developing innovative vaccine strategies, particularly for respiratory diseases including tuberculosis, influenza, and most recently, COVID-19.
Dr. Xing's educational background includes:
- MD in Medicine from North Sichuan Medical College, China (1981)
- MSc in Anatomic Pathology from Tongji Medical University, China (1985)
- PhD in Immunology from McMaster University, Canada (1993)
Dr. Xing conducts bench-to-human translational research with a primary focus on respiratory mucosal immunity, innate memory and trained innate immunity, adaptive memory and T cell immunity. His work spans vaccine development for tuberculosis, influenza, pneumococcal infection, and most notably, his team developed an inhaled COVID-19 vaccine that has progressed through multiple clinical trials. His research has resulted in over 200 publications with more than 22,000 citations, with work appearing in top journals including Cell, Nature Immunology, Nature Communications, and Science Translational Medicine.
Analysis of Dr. Xing's recent publications reveals a strong emphasis on next-generation vaccine technologies, particularly inhaled and dry powder formulations. His work bridges fundamental immunology with practical vaccine development, focusing on mucosal immunity as a critical component of protection against respiratory pathogens. A significant portion of his research explores trained innate immunity and its role in providing broad protection against multiple pathogens. The progression from basic immunology studies to clinical applications demonstrates the translational nature of his research program.
Dr. Xing leads an active research program that has secured substantial funding for vaccine development, particularly for the inhaled COVID-19 vaccine platform (AeroVax) which has progressed from preclinical studies to Phase 2 clinical trials. His work on tuberculosis vaccines represents a decades-long commitment to developing better prevention strategies against this global health threat. The Canadian Pandemic Preparedness Hub features his research, highlighting its importance for future pandemic response.
Dr. Xing teaches advanced courses in immunology and vaccinology at McMaster University, including 'Vaccines and Vaccine Immunology' (MEDSCI 717) and 'Advanced Immunobiology I' (MEDSCI 715), mentoring the next generation of immunologists and vaccinologists. His laboratory continues to investigate fundamental immunological mechanisms while advancing practical vaccine solutions for global health challenges.
