Yongqing Li

Yongqing Li is an Associate Professor in General Surgery Administration at the University of Michigan, with a focus on understanding and targeting protein post-translational modifications in sepsis and traumatic injuries. His research bridges molecular immunology with clinical applications.

• Primary Affiliation: University of Michigan, Department of General Surgery
• Key Collaborators: Hasan Alam, Katsuo Kurabayashi, Jifeng Zhang

Research Interests

Dr. Li's work centers on:

• Peptidylarginine Deiminase (PAD) enzymes and their role in sepsis and immune dysfunction
• Neutrophil Extracellular Traps (NETs) in inflammation and organ injury
• Therapeutic strategies for acute lung injury and traumatic brain injury
• Epigenetic modulation via histone deacetylase (HDAC) inhibitors

Publication Trends

His recent publications (2025–2021) highlight:

• Targeting Citrullinated Histone H3 (CitH3) for sepsis diagnostics
• Developing PAD2 inhibitors to mitigate inflammation
• Investigating macrophage polarization in acute lung injury
• Translating extracellular vesicle therapies for neuroprotection

These works span immunology, molecular biology, and surgical research, with applications in critical care and trauma recovery.