Yingjie Chen

Yingjie Chen is Professor of Physiology at the University of Mississippi Medical Center, specializing in heart failure mechanisms and inflammatory pathways. His NIH-funded research examines cardiac/lung inflammation interactions and developmental programming of cardiovascular disease.

Research focuses on molecular pathways driving heart failure progression, including T-cell regulation, oxidative stress, and dimethylarginine metabolism. Key discoveries include identifying lung inflammation as a driver of right ventricular hypertrophy and establishing DDAH1 as the primary enzyme for ADMA degradation.

Articles consistently demonstrate innovative methodologies in cardiac pathophysiology, with recent work emphasizing immunomodulation, environmental stressors, and metabolic reprogramming. Awards include the Dr. Marvin and Hadassah Bacaner Research Award and Scientist Development Award from AHA.