معرفی
Yibo Xi is an Associate Research Scientist in the Department of Pathology at Yale School of Medicine, Yale University. His research focuses on molecular mechanisms underlying protein aggregation diseases, cancer biology, and epigenetic changes induced by environmental exposures. He holds a PhD from Lanzhou University and completed postdoctoral training at Tsinghua University and the University of Pittsburgh.
Key research interests include cataract formation caused by crystallin protein mutations, retinitis pigmentosa linked to misfolded rhodopsin, and hepatocellular carcinoma driven by fatty acid metabolism dysregulation. He has explored therapeutic strategies such as pharmacological chaperones and small molecules like 8-aminoguanine for age-related retinal degeneration.
Recent work investigates nicotine-induced epigenetic changes in e-cigarette-exposed mice and the role of ACSM5 in liver cancer progression. Collaborations with researchers like Kien Pham and Guilin Wang highlight interdisciplinary approaches to understanding disease mechanisms and developing novel treatments.
