Yang Du

Yang Du is an Associate Professor in the Department of Pediatrics at Uniformed Services University of the Health Sciences, focusing on molecular mechanisms of leukemia development and stem cell self-renewal. His research integrates mouse genetic models and molecular biology techniques.

• Education:
• Ph.D. in Cell Biology and Biochemistry (2000), Texas Tech University Health Sciences Center
• Research Interests:
  • Investigates leukemia oncogenesis through transcriptional regulation and epigenetic modifications
  • Studies roles of genes like SETBP1, HOX families, and RUNX1 in myeloid malignancies
  • Develops mouse models for understanding leukemogenic pathways
• Scientific Contributions:
  • Published extensively in top journals (Leukemia, Blood, Nature Genetics, Oncotarget)
  • Key findings on SETBP1 mutations and their interactions in leukemia progression
  • Contributed to understanding epigenetic repression in leukemogenesis
• Awards:
  • Fellows Award for Research Excellence (FARE), NIH (2005)
  • Faculty Award, TTUHSC (1998)
• Collaborations:
  • Worked with Dr. Neal Copeland and Dr. Nancy Jenkins at NCI-Frederick
  • Collaborates with hematologists and geneticists on translational studies