معرفی
Xuejuan Tan is a Research Assistant Professor in the Department of Biochemistry and Molecular Biology at Oklahoma State University. She holds a B.S. in Food Science and Technology from Huazhong Agricultural University (2002) and a Ph.D. in Microbiology (2009) from the same institution. Her research focuses on understanding host immune responses to mycobacterial infections, with a particular emphasis on extracellular vesicles, host-pathogen interactions, and the role of noncoding RNAs in infectious diseases. She has held postdoctoral positions at the Harper Cancer Research Institute (University of Notre Dame) and Hsiri Therapeutics, before joining Oklahoma State University in 2023.
Her work explores mechanisms of mycobacterial survival within macrophages, antibiotic resistance, and the development of novel vaccines (e.g., a dual vaccine targeting SARS-CoV-2 and Mycobacterium tuberculosis). She has also contributed to studies on cancer metastasis and drug discovery, leveraging systems biology and proteomics approaches.
Recent articles highlight her investigations into how mycobacterial infections modulate macrophage activation via microvesicles, the role of iron metabolism in aging-related susceptibility to infections, and the therapeutic potential of host-directed therapies. Her research bridges microbiology, immunology, and molecular biology, with implications for combating antimicrobial resistance and infectious diseases.
