
معرفی
Dr. Xuebin Yang is an Associate Professor in Stem Cell Therapy and Tissue Engineering at the University of Leeds School of Dentistry, Faculty of Medicine and Health. He serves as the Deputy Pro Dean: International for the Faculty of Medicine and Health and the School Internationalisation Lead for the School of Dentistry. Dr. Yang also holds honorary/visiting professor positions at Nanjing University, Henan University of Science and Technology, Polytechnic Institute of Leiria, and Tokyo Women's Medical University.
Dr. Yang received his first degree in medicine from Luoyang Institute of Science and Technology (formerly Luoyang University) in 1984 and an MSc degree in hand surgery from Fudan University (formerly Shanghai Medical University) in 1992. After obtaining a PhD in tissue engineering from the University of Southampton in 2002, he was appointed to a University Research Fellowship at the University of Leeds School of Dentistry in 2004.
His research focuses on using human mesenchymal stem cells (from bone marrow, dental pulp, periodontal ligament and adipose tissue) and biomaterials scaffolds (PLA/PLGA, silk, BioGlass, glass ceramics, 3D printed scaffolds, hydrogel) for skeletal tissue engineering (bone, cartilage, osteochondral, dental pulp, dentine, periodontal tissues) both in vitro and in vivo. In collaboration with biologists and material scientists, he works on using signaling pathways, genetic and epigenetic approaches for controlling stem cell functionality and developing biomimetic, functional scaffolds for tissue engineering applications.
Analysis of Dr. Yang's recent publications reveals a strong focus on epigenetic regulation of stem cells for bone regeneration, with particular emphasis on the HDAC inhibitor MI192. His work spans biomaterial development (particularly silk-based scaffolds), vascularization of engineered tissues, and innovative approaches to dental and skeletal tissue engineering. The publications demonstrate a progression from fundamental stem cell biology to increasingly translational research with clinical applications.
- University Research Fellowship at the University of Leeds School of Dentistry (2004)
- Head of Tissue Engineering Research (2005)
- Principal Research Fellow (2006)
- Treasurer/Trustee of British Orthopaedic Research Society
- Committee Member of regional/national/international panels
- Chair for prestigious conferences (BORS, TERMIS WC/AP/EU)
Dr. Yang has supervised 12 Masters students, 23 PhD students (including co-supervising students at King's College London, Imperial College London and University of York), and 11 Postdoctoral or visiting Fellows in stem cell therapy and skeletal tissue engineering. He has secured significant research funding from organizations including The Royal Society, Bone Cancer Research Trust, The British Council, Welcome Trust, and EU FP7. His current research involves multiple international consortia with partners in the USA, Australia, New Zealand, Japan, China, Korea, India, and EU countries, as well as strong collaborations with industry partners in the UK, USA, Israel, and China.
Dr. Yang leads the Tissue Engineering initiative at the School of Dentistry and is actively involved in large research programmes including WELMEC, DTC, CDT, LMBRU, Regener8, and IKC. His laboratory focuses on developing innovative approaches to skeletal tissue engineering using biomimetic scaffolds and epigenetically-modulated stem cells.
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