معرفی
Dr. Xin Zhou is an Oxford-Bristol Myers Squibb Fellow at the Department of Computer Science, University of Oxford. Her research integrates computational modeling, clinical data, and experimental findings to investigate cardiac disease mechanisms and develop human-based simulations for drug evaluation.
- BSc and MSc in Life Sciences, Beijing Normal University
- DPhil in Computational Biology, University of Oxford
Her work focuses on multi-scale cardiac modeling, particularly in ischemic heart disease and heart failure, exploring ionic currents, tissue conduction, and organ-level dynamics. She develops electromechanical simulations to study cardiac alternans and arrhythmic risks, translating these into clinical applications for patient stratification and pharmaceutical testing.
Recent publications emphasize in silico clinical trials, sex-specific cardiometabolic analysis, and Purkinje network modeling. Collaborative efforts with clinicians and pharmaceutical partners highlight her translational approach to regulatory science.
- Model of the Year 2024, BioModels
- EPSRC Impact Acceleration Account
- Microsoft Research Project Award
- Recognition Award, University of Oxford
She supervises PhD and MSc students in computational cardiology, while serving on the editorial board of Frontiers in Physiology. Her current projects involve digital twinning and predictive cardiac safety models to reduce animal testing reliance.