Xin Wu

Xin Wu, MD is an Adjunct Assistant Professor and Research Assistant Professor in the Department of Neuroscience & Experimental Therapeutics at Texas A&M University's School of Medicine. His work focuses on mechanotransduction pathways in cardiovascular and neuronal systems, integrating advanced techniques like atomic force microscopy and electrophysiology. Dr. Wu holds dual appointments in cardiology and neuroscience research.

Education: MD from Nantong Medical College (1985), MS in Medical Physiology from Suzhou Medical College (1993).

Research Interests:

• Mechanical stress effects on ion channels
• Integrin-mediated signaling in neurons and cardiomyocytes
• Epilepsy mechanisms and neurosteroid therapies
• Drug development for refractory seizures
• ECM-integrin interactions in disease

Technical Expertise:

• AFM-based cellular mechanics analysis
• In vivo electrophysiology and imaging
• Single-cell isolation techniques
• Lymphatic/vascular modeling
• LC-MS/MS drug analysis

Laboratory Focus: Cardiomyocyte mechanosensitivity, neuronal plasticity in epilepsy, and translational neuropharmacology. Current projects explore sex differences in antiseizure efficacy and novel neuroprotectant development.