معرفی
Xin Chen is a Professor and HHMI Investigator in the Department of Biology at Johns Hopkins University (Krieger School of Arts & Sciences). Her research focuses on epigenetic regulation in adult stem cell lineages, particularly the asymmetric inheritance of epigenetic information during cell division.
Dr. Chen received her Ph.D. in Molecular Cell & Developmental Biology from the University of Texas at Austin, studying Drosophila eye development. She completed postdoctoral training at Stanford University, investigating germ cell differentiation mechanisms under Dr. Margaret Fuller.
Key research areas include histone inheritance asymmetry in stem cells, roles of DNA replication and mitosis in epigenetic partitioning, and the interplay between epigenetic regulators and developmental signaling pathways. Her work employs Drosophila and mammalian models, combining molecular genetics, live-cell imaging, and computational approaches.
Recent publications highlight breakthroughs in understanding how histone distribution patterns influence stem cell fate decisions, with implications for regenerative medicine and cancer biology. Dr. Chen’s HHMI Investigator status underscores her impactful contributions to the field of epigenetics.
Her lab is located in Levi Hall at Johns Hopkins, with active collaborations exploring super-resolution microscopy and chromatin dynamics. No formal advisee list is provided, though her lab trains graduate students and postdoctoral scholars in stem cell and epigenetic research.
