معرفی
Dr. Xiaojiang Chen is a Professor at the University of Southern California, holding appointments in the Departments of Biological Sciences and Chemistry. He is also the Director of the Center of Excellence in NanoBiophysics and a member of the Norris Cancer Center.
Dr. Chen earned his Ph.D. in Biochemistry and Molecular Biology from the University of California, Davis, and completed postdoctoral training at Harvard University. His research spans cancer biology, immunology, virology, and structural biology, focusing on DNA replication/repair enzymes, APOBEC deaminases, and viral oncoproteins.
- Cancer Biology: Investigates DNA-modifying enzymes in genomic instability and tumor suppression.
- Immunology: Studies APOBEC3G and CR2-C3d interactions in antiviral defense.
- Virology: Analyzes HIV, HPV, and SARS-CoV-2 protein structures for therapeutic targets.
- Nanobiophysics: Develops protein nanoparticles for gene delivery.
His recent publications highlight structural insights into APOBEC3G/3H and Polθ, with implications for cancer therapy and HIV restriction. He has received prestigious awards including AAAS Fellowship and Howard Hughes Medical Institute support.
- Scientific Awards:
- AAAS Fellow (2017)
- American Cancer Society Young Investigator (2003)
- Howard Hughes Medical Institute Junior Faculty Award (2000)
- Grants: NIH R01 grants on DNA repair and APOBEC3G structure-function.
