معرفی
Xiao-Lan CHEN is an Associate Professor (Vice Professor) at the College of Chemistry and Chemical Engineering, Xiamen University, Fujian Province, China. Since completing her PhD at Xiamen University in 2001, she has continuously served her alma mater, first as lecturer (2001-2003) and then as Associate Professor from 2003 onward. In 2007-2008 she was a Visiting Scholar at the University of Florida, broadening her international research exposure.
Education
- 1998–2001 PhD, Xiamen University
Research Interests
Her work centers on the design, synthesis and surface engineering of two-dimensional nanomaterials—especially palladium-based nanosheets and hybrid structures—for advanced biomedical applications. Major themes include:
- Multimodal cancer therapy: integrating photothermal, photodynamic and immunotherapy to overcome tumor hypoxia and drug resistance.
- Antibacterial nanomedicine: leveraging plasmonic heating, silver ion release and enzyme-mimetic activity to fight multidrug-resistant infections.
- Theranostic nanoplatforms: developing imaging-guided therapy systems that combine diagnostics (NIR fluorescence, photoacoustic imaging) with therapeutic functions.
- In vivo biocompatibility & biodistribution: comprehensive toxicological evaluation of nanomaterials in small animals to facilitate clinical translation.
Publication Trends
Over 2009-2020 Dr. Chen has authored 18 peer-reviewed articles in leading journals such as ACS Nano, Nanoscale, Advanced Functional Materials and Chemical Science. Her recent work (2017-2020) shows a clear pivot toward synergistic therapeutic strategies that combine photothermal/photodynamic modalities with immunotherapy or antibacterial treatments, frequently employing Pd-based or Pd@Au nanostructures as core platforms.
Scientific Awards & Honors
No specific awards were mentioned in the provided text.
Advising & Collaborative Grants
She has mentored a large cohort of graduate students whose names appear as co-authors across the listed publications, indicating an active research group. Collaborative projects with Nanfeng Zheng, Gang Liu, Jian Weng and others show sustained multi-institutional funding, although specific grant numbers are not provided.
Laboratory & Team
Dr. Chen leads a research laboratory within the College of Chemistry and Chemical Engineering, equipped for nanomaterial synthesis, in vitro cell assays, small-animal imaging and toxicological evaluation. The team routinely collaborates with the National Institute for Nanotechnology and overseas partners such as the University of Florida.
