Wim Mulders

Wim Mulders is a researcher in the Mycobacteriology unit at the Institute of Tropical Medicine Antwerp (ITM), Belgium, with a focus on tuberculosis drug resistance mechanisms. His work spans molecular diagnostics, antimicrobial susceptibility testing, and global health applications, particularly in high-burden regions like the Democratic Republic of Congo and Armenia.

His research interests center on antimicrobial resistance in Mycobacterium tuberculosis, with expertise in bedaquiline, linezolid, and delamanid resistance mechanisms. Key areas include:

• Molecular genetics of resistance markers (e.g., mmpR5/Rv0678)
• Phenotypic-genotypic resistance correlation
• Diagnostic accuracy of Xpert MTB/RIF Ultra
• Global epidemiology of drug-resistant TB
• Quality control in antimicrobial susceptibility testing

Recent work emphasizes resolving discrepancies in bedaquiline resistance phenotypes through structural biology and systematic MIC analysis.

Collaborations span international institutions across the Great Lakes Region, Armenia, and European research networks, with publications in Antimicrobial Agents and Chemotherapy, Clinical Infectious Diseases, and BMC Infectious Diseases. His fingerprint highlights dominant expertise in tuberculosis (100%), Clofazimine (49%), Agar (48%), Great Lakes Region epidemiology (47%), and pretomanid (44%).

Mulders operates within ITM's Mycobacteriology research infrastructure, contributing to laboratory-based studies on TB diagnostics and resistance mechanisms through active field collaborations in resource-limited settings.