William Swindell

William Swindell, D.O., Ph.D., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center, affiliated with its Hospital Medicine Division. His clinical expertise spans general internal medicine, geriatric medicine, and endocrinology. He holds a bachelor's and Ph.D. in biology from Bowling Green State University, a master's in statistics from Michigan State University, and a medical degree from Ohio University Heritage College of Osteopathic Medicine. Postdoctoral training included roles at the University of Michigan, Brigham & Women's Hospital, and Harvard Medical School.

Dr. Swindell's research focuses on bioinformatics, health data analytics, inflammatory mechanisms of aging, and amyotrophic lateral sclerosis (ALS). His work has yielded over 100 peer-reviewed publications, addressing topics like epidermal barrier dysfunction, psoriasis pathogenesis, and anti-inflammatory agents. He is an active member of professional organizations including the American College of Physicians and Texas Medical Association.

His research has explored synergistic anti-inflammatory effects of novel compounds (e.g., isosorbide di-(methyl fumarate)), gene expression patterns in systemic sclerosis, and mechanisms linking inflammation to skin aging. Collaborative efforts have led to discoveries in psoriasis, atopic dermatitis, and epidermal differentiation pathways.

Dr. Swindell's work bridges translational medicine and clinical practice, with recent emphasis on developing topical treatments for skin disorders and understanding aging-related inflammation. His contributions span basic science to clinical applications, reflecting a commitment to improving patient outcomes through data-driven research.