Wade M. Mueller

Wade M. Mueller, MD, is a Professor in the Department of Neurosurgery at the Medical College of Wisconsin. He specializes in neurosurgical treatments for malignant brain tumors and epilepsy, with expertise in functional brain mapping, awake surgery techniques, and advanced neuroimaging. His clinical affiliations include Froedtert Hospital and the Zablocki Veterans Medical Center. He earned his MD from the University of Wisconsin Medical School and completed neurosurgical training at the Medical College of Wisconsin, supplemented by fellowships in epilepsy surgery and spinal cord injury at the University of Washington and Zablocki VA Medical Center.

His research focuses on improving surgical outcomes through innovations in neuroimaging (e.g., T1 mapping, fMRI) and functional connectivity analysis, with particular emphasis on glioblastoma biology and epilepsy surgery optimization. Over 10+ peer-reviewed articles in 2023-2025 highlight his contributions to tumor invasion mapping, seizure localization via EEG, and radiation therapy outcomes for metastatic brain lesions. Collaborations span neuro-oncology, neuroimaging, and cognitive neuroscience.

No scientific awards are explicitly noted in the provided texts. His clinical programs include Brain & Spine Tumor Program and Epilepsy Program. He maintains board certification in Neurological Surgery from the American Board of Neurological Surgery.

Research and clinical work emphasize translational applications of imaging technology to neurosurgical decision-making, including awake craniotomy neuronavigation and postoperative survival prediction models. His work integrates molecular pathology (e.g., mesenchymal mutations in glioblastoma) with clinical outcomes analysis.