
Vivien Bothe
پژوهشگر · Regenerative Biology
Leibniz Institute for Research on Evolution and Biodiversity at the Humboldt University Berlinمعرفی
Vivien Bothe is a Post-Doc Researcher at the Museum of Natural History, Leibniz Institute for Evolution and Biodiversity Research in Berlin, working under Prof. Nadia Fröbisch's research group. Her work bridges paleontological and contemporary biological data to investigate evolutionary mechanisms.
Her research focuses on regenerative biology through a deep-time evolutionary lens, examining limb and tail regeneration across tetrapods. Key methodologies include histological analysis of fossil and extant specimens, with primary models being salamanders (Ambystoma tigrinum), axolotls (Ambystoma mexicanum), and lungfish. She investigates how life history strategies, metamorphosis, and nervous system interactions influence regenerative capacity.
Recent publications reveal trends in comparative regenerative mechanisms across species, emphasizing the role of peripheral nervous systems in stem cell activation and how metamorphic processes constrain regenerative diversity. Her work integrates paleontological evidence with experimental developmental biology to reconstruct evolutionary trajectories of regeneration.
Bothe operates within Prof. Fröbisch's research infrastructure at the Museum für Naturkunde, utilizing specialized histology and imaging facilities for both fossil specimens and live animal models. Her collaborative projects span international institutions, focusing on evolutionary constraints in regenerative processes.
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