Victor Greiff

Victor Greiff is a Professor at the University of Oslo's Institute of Clinical Medicine, leading the Computational and Systems Immunology group. His research focuses on integrating high-throughput single-cell sequencing, artificial intelligence, and high-dimensional statistics to advance therapeutic antibody design, diagnostics, and vaccine development for infectious diseases, autoimmunity, and cancer.

• Key Research Areas: Computational immunology, adaptive immune receptor repertoires, machine learning in antibody discovery, bioinformatics, structural biology, and immune diagnostics.
• Funding: European Research Council (ERC) Grant AB-AG-INTERACT (Project ID: 101125630).

Recent Publications highlight interdisciplinary work in:

• Machine learning for antibody design and immune repertoire classification.
• Structural analysis of antibody-antigen interactions and evolutionary immunogenetics.
• Development of bioinformatics tools (e.g., ExpoSeq, TCRpower, CompAIRR) for immune sequencing data analysis.

Scientific Contributions include:

• Establishing computational frameworks for synthetic immune repertoire generation.
• Exploring genetic constraints on TCR and BCR diversity.
• Advancing AI-driven antibody engineering for improved therapeutic developability.