معرفی
Veronique Lacombe is a Professor in the Department of Physiological Sciences at Oklahoma State University's College of Veterinary Medicine. She also holds adjunct professor positions in the Department of Biochemistry and Molecular Biology at Oklahoma State University and in the Department of Physiology at the University of Oklahoma Health Sciences Center. Dr. Lacombe serves as Vice-Chair of the Graduate Council at Oklahoma State University and directs the Comparative Metabolism Research Laboratory.
Dr. Lacombe earned her DVM from the National Veterinary School of Maisons-Alfort near Paris, France, followed by a residency in large animal internal medicine at The Ohio State University College of Veterinary Medicine. She completed her PhD in Comparative Exercise Physiology at The Ohio State University and a postdoctoral fellowship at the College of Pharmacy. She is a Diplomate of both the American College of Veterinary Internal Medicine (Large Animal) and the European College of Equine Internal Medicine.
Her research focuses on glucose metabolism, particularly examining how diabetes and viral infections affect glucose transport mechanisms in various tissues. Her laboratory investigates the relationship between insulin sensitivity and cardiac function, equine metabolic syndrome, and the impact of viral infections like influenza and SARS-CoV-2 on whole-body glucose homeostasis. She has made significant contributions to understanding the role of glucose transporters (GLUTs) in the lung, heart, and other tissues during disease states.
Analysis of her recent publications reveals a strong trend toward translational research connecting basic metabolic mechanisms with clinical outcomes. Her work spans multiple disciplines including veterinary medicine, human diabetes research, virology, and cardiovascular physiology, with a particular emphasis on the One Health approach that connects animal and human health. Her research demonstrates how metabolic alterations during diabetes increase susceptibility to respiratory infections and how viral infections themselves can reprogram host metabolism.
- Oklahoma Center for Respiratory and Infectious Diseases (NIH-funded CoBRE)
- One Health Collaborative Seed Grant Program
- Oklahoma Center for the Advancement of Science and Technology (OCAST)
- American Heart Association
- National Center for Advancing Translational Sciences
Dr. Lacombe actively mentors graduate students through PhD Research and Dissertation courses and teaches Pharmacology I. Her Comparative Metabolism Research Laboratory employs innovative approaches including euglycemic-hyperinsulinemic clamps, proteomic analyses, and specialized techniques for measuring glucose transporter translocation to investigate metabolic pathways in both animal models and clinical settings. Her research has important implications for understanding and treating metabolic complications in both human and veterinary medicine.
