Urszula Ledzewicz

Prof. Urszula Ledzewicz is a Research Professor in the Department of Mathematical Modeling at Lodz University of Technology with an extensive publication record spanning several decades. She has established herself as a leading researcher in the application of mathematical modeling and optimal control theory to cancer therapy.

Her research focuses on:

• Mathematical oncology and tumor dynamics
• Optimal control theory applied to cancer treatments
• Pharmacometrics in chemotherapy modeling
• Combination therapies (chemo-, immuno-, anti-angiogenic)
• Tumor-immune system interactions
• Mathematical modeling of drug resistance

Dr. Ledzewicz's publication record demonstrates a consistent focus on developing sophisticated mathematical models for optimizing cancer treatment protocols. Her recent work (2020-2025) shows an increasing emphasis on combination therapies, particularly exploring the synergy between chemotherapy and immunotherapy. She has co-authored numerous papers with Heinz Schättler, focusing on rigorous mathematical approaches to treatment optimization.

She has served as a PhD advisor for Maciej Leszczyński (2019) and Elżbieta Ratajczyk (2017), whose dissertations focused on mathematical models of cancer therapy with pharmacometrics and glioma treatment optimization, respectively.

Dr. Ledzewicz has also contributed to special editions honoring prominent mathematicians like Avner Friedman and has co-authored significant books including "Optimal Control for Mathematical Models of Cancer Therapies - An Application of Geometric Methods" (Springer, 2015) and "Geometric Optimal Control: Theory, Methods, Examples" (Springer, 2012).