Tomohisa Toda

Prof. Dr. Tomohisa Toda serves as a Group Leader at the German Center for Neurodegenerative Diseases (DZNE) in Dresden, Germany, where he leads research on the biological links between aging and neurological disorders.

His primary research interests encompass aging mechanisms, neurodegenerative diseases, and nuclear architecture in neural cells. Specifically, Dr. Toda investigates how nucleoporins and nuclear lamins establish cell type-specific nuclear organization to maintain neural identity and plasticity throughout life. His laboratory employs mouse models and stem cell biology to dissect the molecular pathways that deteriorate during pathological aging.

Dr. Toda's publication record includes significant contributions such as a 2017 Cell Stem Cell paper demonstrating nucleoporins' role as structural gatekeepers for neural identity. His work spans broad disciplines including neuroscience, cell biology, and aging research, with specific focus on nuclear pore complex dynamics, transcription factor networks, and age-related protein damage in the brain.

The Toda laboratory at DZNE Dresden is dedicated to uncovering fundamental principles of neural maintenance and how their disruption leads to disease, utilizing interdisciplinary approaches to address critical questions in brain aging and neurodegeneration.