Toloo Taghian

Toloo Taghian is an Instructor in the Department of Genetic and Cellular Medicine at the University of Massachusetts Chan Medical School, affiliated with the T.H. Chan School of Medicine. She holds additional positions in the Gene Therapy Center, Genetic and Cellular Medicine, and Radiology departments within the same institution.

Education:
- BS and MS in Physics, Isfahan University of Technology, Iran
- PhD in Physics, University of Cincinnati, USA

Research Focus:
Dr. Taghian's work centers on gene therapy, neurodegenerative diseases, molecular biology, and biomedical engineering. Her research employs animal models to study conditions like Huntington’s disease, Tay-Sachs disease, and metabolic disorders. She explores advanced delivery techniques for gene therapy vectors and imaging technologies to monitor therapeutic efficacy.

Key Contributions:
- Developed minimally invasive CNS delivery methods for AAV vectors
- Advanced understanding of synaptic protein changes in Huntington’s disease models
- Investigated electric field modulation of cellular functions

Labs/Teams:
She contributes to interdisciplinary teams in gene therapy, neuroimaging, and vascular biology at UMass Chan Medical School.