معرفی
Dr. Todd Markham is a Research Fellow at the University of Sydney's School of Medical Sciences, Faculty of Medicine and Health, working under Prof. Rachel Codd. His research focuses on synthetic organic chemistry, medicinal chemistry, and chemical biology, particularly in developing metal chelators inspired by microbial siderophores and modifying natural products like pyrethrins.
Education:
- B.Sc. (Hons.) in Forensic and Analytical Sciences from Flinders University (2016)
- Ph.D. in collaboration with CSIRO (2021), supervised by Assoc. Prof. Martin Johnston and Prof. Peter Duggan, focusing on site-selective synthetic modifications of pyrethrins.
Research Highlights: Specializes in siderophore-based chelation systems, enzymatic synthesis of hydroxamic acid derivatives, and forensic analysis of illicit substance manufacturing. His work bridges organic synthesis with biological applications, including insecticide development and protein purification techniques.
Publications: Recent work includes breakthroughs in siderophore synthetase mechanisms (2025) and modular desferrioxamine synthesis (2024), reflecting a trend toward interdisciplinary chemical biology and medicinal chemistry.
- Awards: 2024 Centre for Drug Discovery Innovation Early Career Researcher Excellence Award
Advising & Collaborations: Supervises Samuel Feeney (evaluating metal chelators) and Joseph Wang (enzyme-mediated chelator design). Collaborates with institutions like CSIRO on natural product chemistry projects.
Labs/Teams: Part of the Medical Sciences research group at the University of Sydney, contributing to drug discovery and chemical biology initiatives.
