Tim Wiltshire

Dr. Tim Wiltshire is an Associate Professor at the University of North Carolina at Chapel Hill School of Pharmacy, where he conducts research in pharmacogenetics and personalized medicine. He leads the Wiltshire Laboratory and is affiliated with the UNC Institute for Pharmacogenomics and Individualized Therapy (CPIT). His work focuses on translating pharmacogenetic knowledge into clinical practice to improve medication safety and efficacy.

Dr. Wiltshire's research spans multiple areas of pharmacogenomics, with particular emphasis on:

• Predicting drug response and adverse events using genetic information
• Developing clinical implementation strategies for pharmacogenetic testing
• Personalized dosing approaches for medications across various therapeutic areas
• Pharmacogenomic applications in vulnerable populations including nursing home residents
• Translating pharmacogenetic findings into clinical practice guidelines

His recent publications demonstrate a strong focus on applying pharmacogenomics to cancer therapy, transplant medicine, and cardiovascular care. Dr. Wiltshire's work often involves multi-institutional collaborations, particularly through the North Carolina Precision Health Collaborative, which aims to implement pharmacogenomics across healthcare systems in North Carolina.

Among his notable scientific contributions are:

• Development of prediction models for chemotherapy-induced toxicity
• Research on pharmacogenomic applications in hematopoietic stem cell transplant
• Studies examining the feasibility of pharmacogenetics in nursing home settings
• Work on rare genetic variants affecting drug metabolism

Dr. Wiltshire has received research funding for his work in pharmacogenomics implementation and has contributed to educational initiatives in precision medicine. His laboratory collaborates with clinicians across multiple specialties to translate pharmacogenetic knowledge into practical clinical applications that improve patient outcomes.