Thomas Ostenfeld Larsen

Thomas Ostenfeld Larsen is Professor at the Technical University of Denmark's Department of Biotechnology and Biomedicine, specializing in natural products chemistry from microorganisms. His research focuses on bioactive compounds from fungi and other microorganisms with applications in drug discovery and biotechnology.

Research interests include natural products chemistry, fungal genomics, and microbial biotechnology. His work emphasizes discovery of novel bioactive compounds, structural characterization of secondary metabolites, and investigation of biosynthesis pathways.

Recent publications demonstrate innovations in fungal genomics, discovery of anticancer compounds from microbial sources, and characterization of algal toxins. Studies highlight molecular mechanisms of natural products against cancer stem cells and toxicological profiles of harmful algal metabolites.

Leads projects on genome mining for natural products, including discovery and engineering of carbohydrate-active enzymes. Research extends to fish skin waste valorization for precision prebiotics and marine toxin characterization.

International collaborations include research on phytopathogens and microbial secondary metabolism. His team uses metabolomics-guided approaches for natural product discovery and develops engineered microbial therapeutics.