Thomas Manning

Dr. Thomas Manning is a Professor at Valdosta State University teaching Instrumental Analysis, Environmental Chemistry, Physical Chemistry, and marine-related courses. His research bridges pharmaceutical innovation and marine ecosystem restoration, with significant contributions to drug development for cancer, infectious diseases, and neurological disorders.

Education:

• B.S. in Chemistry, College of Charleston
• M.S. in Chemistry, University of Florida
• Ph.D. in Chemistry, University of Florida

His primary research focuses on metal-based drug complexes, yielding 20 pre-clinical candidates at the National Cancer Institute, a patented multidrug-resistant tuberculosis treatment, and novel COVID-19 therapies. Concurrently, he leads oyster and coral restoration projects applying chemical defense systems and nutrient substrates to marine rehabilitation. His work integrates medicinal chemistry with environmental science to address therapeutic and ecological challenges.

Recent publications (2025-2016) reveal consistent themes: copper/iron complexes enhancing drug efficacy against cancer and infections (e.g., paclitaxel-copper crystals, isoniazid repurposing), inhalation therapies for tuberculosis/COVID-19, and microbial-nutrient systems for marine restoration. These span pharmaceutical chemistry, virology, and marine ecology, demonstrating translational applications from antiviral agents to coral reef rehabilitation.

Dr. Manning mentors undergraduate researchers in his lab, producing patented drugs and pre-clinical candidates through National Cancer Institute collaborations. His marine restoration projects involve field implementation of microbial coatings and mineral substrates for oyster/coral rehabilitation, supported by university resources and interdisciplinary partnerships.

Based in Bailey Science Building #3076, his research group leverages university facilities for drug synthesis and marine ecosystem studies, maintaining active projects in pharmaceutical development and coastal habitat restoration through undergraduate-driven innovation.