Thomas Eschenhagen

Professor Thomas Eschenhagen is a distinguished researcher at the Institute of Experimental Pharmacology and Toxicology at Universitätsklinikum Hamburg-Eppendorf. With over 300 publications to his name, his work focuses on cardiovascular research, particularly in the areas of cardiac electrophysiology, stem cell-derived cardiomyocytes, and tissue engineering for heart repair. His research has significant implications for understanding and treating atrial fibrillation, cardiomyopathies, and other cardiac conditions.

Professor Eschenhagen's research interests span multiple interconnected fields of cardiovascular science. His work in stem cell biology has focused on developing human-induced pluripotent stem cell-derived cardiomyocytes as models for studying cardiac electrophysiology and disease. He has made significant contributions to understanding how engineered heart tissue can be used for cardiac repair and regeneration. His pharmacological research has investigated drug targets for atrial fibrillation and other cardiac arrhythmias, with particular attention to phosphodiesterase inhibition and SGLT2 inhibitors. Additionally, his work explores the metabolic aspects of cardiac function and disease, including the role of mitochondrial function and metabolic communication in heart health.

Professor Eschenhagen's recent publications demonstrate a strong focus on translational research that bridges basic science and clinical applications. His work on engineered heart tissue models has provided valuable insights into cardiac electrophysiology and potential therapeutic approaches for heart disease. He has been instrumental in developing human-induced pluripotent stem cell-derived models that accurately recapitulate human cardiac physiology, which has important implications for personalized medicine and drug testing.

Professor Eschenhagen leads a research team focused on cardiac tissue engineering, stem cell biology, and pharmacological approaches to cardiac disease. His laboratory has developed sophisticated models for studying cardiac electrophysiology and testing potential therapeutics for heart conditions.