Thiago Rodrigues

Thiago Rodrigues serves as a Research Fellow at Stony Brook University under Dr. Wali Karzai's mentorship, specializing in structural and molecular biology with emphasis on protein-protein interactions, functional mechanisms, and atomic-level protein structures. His current research employs biochemical and structural methodologies to investigate ribosome-dependent protein quality control pathways in bacterial systems.

His academic foundation includes:

• PhD in Biochemistry and Molecular Biology (2018) from Federal University of Paraná (UFPR), Brazil

Dr. Rodrigues' research program focuses on bacterial signal transduction networks, particularly PII protein regulation of metabolic processes in Escherichia coli and Azospirillum brasilense. His work examines protein interactions with targets including acetyl-CoA carboxylase and ammonium transporters, utilizing proteomic and biochemical approaches to dissect nitrogen regulation, fatty acid biosynthesis, and protein quality control mechanisms. This integrated methodology reveals fundamental principles of microbial adaptation and metabolic homeostasis.

Analysis of his publication record shows a cohesive trajectory in bacterial protein signaling, with consistent application of molecular microbiology techniques to elucidate regulatory mechanisms across seven peer-reviewed articles. The research demonstrates progressive investigation from in vitro protein interactions (2011) to complex proteome dynamics under metabolic stress (2017), establishing significant contributions to understanding microbial signal transduction and its metabolic implications.