معرفی
Terence Ozolins is an Associate Professor in the Department of Biomedical and Molecular Sciences at Queen's University's Faculty of Health Sciences. He holds cross-appointments with the Translational Institute of Medicine (TIME) and teaches courses in pharmacology and toxicology, including PHAR 480: Drug Discovery and Development.
His research focuses on the etiology of ventricular septation defects (VSD) using rat models to understand how environmental influences during gestation cause structural heart defects and long-term postnatal cardiac dysfunction even after spontaneous repair. The lab investigates molecular mechanisms underlying teratogen-induced cardiac malformations and persistent physiological abnormalities.
Publications demonstrate expertise in high-resolution fetal ultrasound imaging, molecular pathways of teratogenesis, and transgenerational effects of chemical exposures. Recent work explores AP-1 transcription factor regulation in embryotoxicity.
Scientific Awards:
- Safety Sciences Award for Scientific Excellence (2003)
Dr. Ozolins maintains collaborations with clinical researchers and previously spent 11 years in pharmaceutical industry research. Current projects examine epigenetic mechanisms in congenital heart defects and developmental origins of adult cardiovascular disease.
