Susan Jean Marriott

Susan Jean Marriott, Ph.D., is a Professor at Baylor College of Medicine in Houston, TX. She holds positions in the Department of Virology & Microbiology and is a member of the Dan L Duncan Comprehensive Cancer Center. Her research focuses on viral transformation and transcription control, particularly the mechanisms by which the HTLV-I Tax protein disrupts cellular processes to promote oncogenesis.

Dr. Marriott received her B.S. from Iowa State University (1981), Ph.D. from Kansas State University (1986), and completed advanced training at the National Institutes of Health (1991).

Her laboratory investigates Tax-mediated dysregulation of DNA repair, cell cycle checkpoints, and chromatin remodeling. Key areas include Tax's interaction with CREB/NF-kB pathways, PCNA overexpression, and its role in fixing mutations during DNA replication. Research emphasizes G1/S checkpoint defects and genomic instability in HTLV-I-associated diseases like adult T-cell leukemia.

Her publications consistently explore HTLV-I virology, Tax protein functionality, DNA damage responses, and oncogenic transformation. Recent work highlights ATM kinase inhibition, ubiquitination dynamics, and nuclear transport mechanisms.

Dr. Marriott leads a research team at Baylor College of Medicine focused on HTLV-I pathogenesis. No awards, grants, or student advisees are detailed in available sources.