Surendra Sharma

Dr. Surendra Sharma serves as Professor in Obstetrics & Gynecology and Adjunct Professor in Pediatrics at the University of Texas Medical Branch School of Medicine, where he directs significant NIH-funded research on pregnancy complications and immunological mechanisms.

His research centers on preeclampsia pathogenesis, investigating inflammatory pathways, placental dysfunction, and novel connections to neurodegenerative disorders through protein misfolding mechanisms. Key interests include interleukin-10 regulation, trophoblast biology, B-cell immunity, and microbiome interactions in reproductive health, with emphasis on translational applications for early detection and intervention.

Recent publications reveal converging trends in proteinopathy/tauopathy pathways linking preeclampsia to dementia, autophagy modulation for therapeutic development, and microbiome dynamics in vaginal infections. His work demonstrates consistent innovation in connecting obstetric complications with systemic physiological processes.

Dr. Sharma currently leads two major NIH projects: an R01 grant from NICHHD (2024-2029) targeting protein degradation therapies for preeclampsia, and an NIAID-funded study (2021-2025) investigating immune-activating microvesicles in preeclampsia pathogenesis, reflecting his dual focus on mechanistic understanding and clinical translation.