Subrata Sabui

Subrata Sabui is an Assistant Professor in the School of Medicine at the University of California, Irvine, affiliated with the Department of Physiology & Biophysics. His research focuses on vitamin transport mechanisms and their roles in maintaining intestinal health.

Research Interests: Sabui investigates nutrient absorption, particularly the sodium-dependent multivitamin transporter (SMVT), using mouse models to study biotin/pantothenic acid deficiency and its link to intestinal inflammation. His work demonstrates that vitamin oversupplementation can reverse growth defects and mucosal abnormalities in SMVT knockout models.

Scientific Trends: Recent publications highlight his contributions to understanding how bacterial toxins (e.g., E. coli), cytokines (IL-1β), and stressors (hypoxia, alcohol) affect vitamin transporters in the gut. This research intersects with microbiome studies, inflammatory bowel disease, and mitochondrial function.

Grants and Collaborations: Sabui's work is supported by NIH grants (R37 DK056061, R01 DK056061, R01 DK058057, R01 AA018071) and VA funding (I01 BX001142), often collaborating with researchers like HM Said and colleagues on transporter biology.