معرفی
Steven Hughes is a Senior Postdoctoral Research Fellow at the University of Oxford, affiliated with the Nuffield Laboratory of Ophthalmology and the Sleep and Circadian Neuroscience Institute. He holds a BSc, MSc, and PhD.
- Research focuses on melanopsin-based signaling pathways in the retina, particularly phototransduction in photosensitive retinal ganglion cells (pRGCs).
- Investigates ion channels' role in melanopsin signaling and pRGC excitability.
- Assesses genetic variations (OPN4 SNPs) and melanopsin-based optogenetic gene therapy for retinal degeneration.
His work intersects neuroscience, molecular biology, and ophthalmology, with key themes including TRPM channels in photoreception, optogenetic vision restoration, and circadian rhythm disruption in neurodegenerative diseases like Huntington's. Collaborations include Mark Hankins and Stuart Peirson.
Scientific contributions span understanding pRGC function, non-image-forming visual pathways, and translational applications in retinal disorders. No formal awards are listed, but his research drives advancements in photoreceptor mechanisms and therapeutic strategies.
