Steven E. Glynn

Steven E. Glynn is an Associate Professor in the Department of Biochemistry and Cell Biology at Stony Brook University. His research focuses on mitochondrial proteostasis, particularly the role of AAA+ proteases in maintaining mitochondrial function through ATP-dependent protein degradation. He investigates how these proteases select substrates from complex cellular environments and utilize nucleotide energy for conformational changes during proteolysis.

Research Interests: Dr. Glynn's work lies at the intersection of mitochondrial biology and enzymology. His lab examines:

• Substrate recognition mechanisms in mitochondrial AAA+ proteases
• Structural dynamics of ATP-driven protein unfolding
• Regulation of mitochondrial proteome through proteostasis networks
• Implications in neurodegenerative diseases and metabolic disorders

Publications reveal a consistent focus on protease mechanisms and mitochondrial function, spanning biochemical analysis, structural biology, and biomedical applications. His recent studies highlight the molecular basis of AFG3L2 protease activity and its relevance to human health.