Steven Carroll

Steven Carroll, MD, PhD, is a Professor and Chair of the Department of Pathology and Laboratory Medicine at the Medical University of South Carolina (MUSC). He holds the Gordon R. Hennigar, Jr., MD Endowed Chair in Pathology and directs the Biorepository & Tissue Analysis Shared Resource at MUSC Hollings Cancer Center, the South Carolina Alzheimer’s Disease Research Center, and the Carroll A. Campbell Jr. Neuropathology Laboratory. His research focuses on neurofibromatosis type 1 (NF1), malignant peripheral nerve sheath tumors (MPNSTs), and neurodegenerative diseases.

• BS in Vertebrate Zoology, Chemistry, and Anthropology, University of Memphis (1981)
• MD and PhD in Cell Biology, Baylor College of Medicine (1986-1988)
• Postdoctoral training in Anatomic Pathology and Neuropathology at Washington University in St. Louis (1988-1994)

His research program investigates growth factor signaling in MPNST pathogenesis, particularly neuregulin-1 (NRG1) and erbB receptors. He explores genetic and epigenetic mechanisms of tumor progression and neurodegeneration, with a focus on R-Ras subfamily proteins and lysophosphatidic acid receptors. His work employs genetically engineered mouse models and human biospecimen networks for translational studies.

Recent publications highlight his expertise in MPNST mouse models (2024), cross-species genomic analysis (2023), and ERBB3's role in oncogenesis (2019). Collaborations include the international Down Syndrome Biobanking Consortium and national biospecimen networks.

• Scientific Awards:
• Fellow of the American Society of Clinical Pathologists (FASCP)
• Fellow of the College of American Pathologists (FCAP)

Dr. Carroll has been continuously funded by the National Institutes of Health (NIH) and Department of Defense (DoD) since 2001. He serves as Associate Editor for the American Journal of Pathology and Journal of Neuropathology and Experimental Neurology, and on the editorial board of Neuro-Oncology. His lab has developed key platforms for neurofibromatosis research and Alzheimer's disease proteomics.