Stephen Pflugfelder

Stephen Pflugfelder, M.D., is a Professor and James and Margaret Elkins Chair in Ophthalmology at Baylor College of Medicine. His clinical and research focus centers on corneal and ocular surface diseases, including corneal transplantation, epithelial stem cell therapy, and surgical innovations for ocular surface reconstruction. He is affiliated with the Cullen Eye Institute and practices at the Alkek Eye Center in Houston, TX.

Education:

• B.A. in Biology (Summa cum laude), Colgate University, 1977
• M.D., State University of New York Upstate College of Medicine, 1981
• Residencies/Fellowships: Ophthalmology, Internal Medicine, and Cornea/External Eye Diseases specialties at Baylor and University of Miami

Research Interests:

Dr. Pflugfelder investigates ocular surface disorders, including dry eye disease mechanisms, corneal transplantation outcomes, and therapeutic interventions for corneal endothelial dysfunction. His work combines clinical practice with laboratory studies on goblet cell biology and immunomodulatory pathways in ocular surfaces.

Publications:

Recent work explores environmental stress effects on ocular surfaces, IL-13-driven goblet cell responses, and dry eye therapy efficacy. These studies emphasize translational research bridging basic science and clinical care.

Grants & Awards:

While no specific awards are listed, his academic rank and endowed chair reflect recognition of his contributions to ophthalmology.