معرفی
Stephanie Dakin is a tenured Full Professor of Musculoskeletal Sciences at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, and a Senior Research Fellow at Green Templeton College. Her research focuses on identifying mechanisms of chronic inflammatory fibrosis in soft tissue joint diseases including tendinopathy, frozen shoulder, and knee arthrofibrosis to develop novel therapeutic strategies for fibrosis resolution.
Her educational background includes:
- BVetMed from the Royal Veterinary College (RVC), University of London (2003)
- PhD from the RVC (completed 2012)
- PGCert in Teaching & Learning in Higher Education (2020)
Professor Dakin's research centers on the cellular and molecular basis of soft tissue joint diseases, investigating how tissue-resident cells including fibroblasts and macrophages drive chronic inflammation and fibrosis. Her work spans from equine orthopaedics to human translational research, with particular emphasis on identifying resolution pathways in inflammatory fibrosis to develop targeted therapies for conditions like frozen shoulder and tendinopathy.
Her publication record (2015-2025) shows a clear evolution from foundational studies on inflammation in tendon disease toward advanced single-cell and transcriptomic analyses of fibrosis mechanisms. Recent work leverages cutting-edge techniques to model soft-tissue diseases in vitro and identify precision therapeutic targets, with growing emphasis on stem cell dynamics and resolution biology in chronic conditions.
Her scientific recognition includes:
- Versus Arthritis Foundation Fellowship
- Oxford-UCB Prize Fellowship in Biomedical Sciences
- Versus Arthritis Career Development Fellowship
- Fellow of the Higher Education Academy
Professor Dakin has supervised multiple research students including Alejandro Gomez, Alexis Pointdexter, and Jiachen Lou, and served as Director of Postgraduate Taught Studies for the MSc in Musculoskeletal Sciences for eight years. Her research is funded by major grants from Versus Arthritis, NIBR Global Scholars program, Oxford-BMS, The Rosetrees Trust, NC3Rs, and UKRI. She leads the Dakin Group (Soft Tissue Joint Disease) at NDORMS, collaborating closely with Professors Andrew Carr, Christopher Buckley, and Mark Coles on translational research aimed at reducing the global burden of soft tissue joint diseases.
