معرفی
Stanislav Kholmanskikh serves as Assistant Professor of Research in Neuroscience at the Brain and Mind Research Institute, Weill Cornell Medical College (Cornell University) since 2013, focusing on molecular mechanisms of neurodevelopmental disorders through cytoskeletal and genetic investigations.
Education:
- Ph.D., University of Minnesota Medical School (2002)
- B.S., Moscow State University, Russia (1997)
Research Focus: His work bridges neuroscience, genetics, and cell biology to elucidate how cytoskeletal regulators (LIS1, Rho GTPases, actin) and gene mutations disrupt neuronal migration. Key discoveries include identifying ACTB/ACTG1 mutations causing Baraitser-Winter syndrome and CCND2 variants driving megalencephaly-polymicrogyria syndromes.
Publication Evolution: Research progressed from foundational neuronal motility studies (2003-2005) to human mutation discoveries (2012-2022), with consistent emphasis on Rho GTPase signaling and cortical malformations. High-impact work in Nature Genetics demonstrates translational relevance to neurodevelopmental diagnostics.
Research Support:
- Co-Investigator on active research grant (2018-2024)
Research Environment: Conducts studies within the Brain and Mind Research Institute, leveraging interdisciplinary neuroscience infrastructure at Weill Cornell Medical College for molecular, genetic, and behavioral investigations.
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