Sreejith Jayasree Varma

Dr. Sreejith Jayasree Varma is an Assistant Professor at the Indian Institute of Science Education and Research Thiruvananthapuram (IISER TVM), leading the MetaChem Lab. His research focuses on metabolic biochemistry, the origin of life, and mass spectrometry-based analytical assays.

• Education: Undergraduate in Chemistry at IISER Pune; PhD in metabolic chemistry at the University of Strasbourg; Postdoctoral research at Charité Universitätsmedizin Berlin.

His work explores carbon-carbon bond-forming reactions in core metabolism, metal ion roles in metabolic evolution, and nonenzymatic metabolic pathways relevant to prebiotic chemistry. Recent publications analyze syntrophic yeast communities, metabolite exchange mechanisms, and metal-catalyzed prebiotic reactions.

The MetaChem Lab develops mass spectrometry techniques to characterize metabolomes and study metabolic network origins. Collaborations span systems biology, bioinformatics, and geochemistry.

Key publications highlight metabolic symbiosis, primordial carbon fixation, and metal-driven reaction efficiency. Research trends emphasize interdisciplinary approaches bridging chemistry, biology, and evolutionary science.