Skirmantas Janusonis

Skirmantas Janusonis is an Associate Professor in the Department of Psychological and Brain Sciences at the University of California, Santa Barbara (UCSB). He is a core faculty member of the UCSB Neuroscience Research Institute and the Interdepartmental Graduate Program in Dynamical Neuroscience, and a member of the California NanoSystems Institute. His research program lies at the intersection of neuroscience, complex systems, and computational modeling.

Education:

• Ph.D. in Neuroscience and Behavior, University of Massachusetts Amherst
• Postdoctoral Research, Department of Neuroscience, Yale University School of Medicine
• B.S./M.S. in Biology, Vilnius University, Lithuania

Dr. Janusonis's research focuses on the stochastic (random walk-like) behavior of serotonergic axons in the brain, particularly within the ascending reticular activating system and the broader serotonergic matrix. His work integrates molecular neurobiology, comparative neuroanatomy (from sharks to rodents to humans), advanced microscopy, and supercomputing simulations. He investigates how these complex systems self-organize and their relevance to mental disorders, especially autism and the enigma of platelet hyperserotonemia. His lab collaborates with physicists, mathematicians, and engineers to model anomalous diffusion and fractional Brownian motion in 3D brain spaces.

His recent publications reveal a strong trend toward computational and theoretical neuroscience, using high-resolution data and mathematical generalizations to model axonal distributions. Key themes include reflected fractional Brownian motion, self-organization of serotonergic densities, and the interface between central and peripheral serotonin systems. His work challenges traditional views of the blood-brain barrier and proposes interdisciplinary solutions involving immunology, physiology, and computer science.

Scientific Awards and Recognition:

• Elected to the Board of Directors of the Organization for Computational Neurosciences (2024)
• NSF, NIMH, and California NanoSystems Institute grant funding
• Multiple student awards under his mentorship, including the Harry J. Carlisle Award and NIH IRTA
• NSF CRCNS and Frontera supercomputing grants
• UCSB Art of Science People's Choice Award (awarded to lab member)

Dr. Janusonis actively mentors PhD students such as Justin Haiman and Dahyana Arroyo, and has advised alumni including Dr. Angela Chen, Dr. Kasie Mays, and Dr. Melissa Hingorani. His lab has received numerous grants from the NSF and NIH, supporting research on stochastic axon systems and super-resolution imaging. He teaches graduate and undergraduate courses including Neuroanatomy (Psy 269), Neurobiology of Brain States (Psy 136), and Complex Systems (Psy 113L).

Research Team and Collaborations: The Janusonis Lab is an interdisciplinary group combining neuroscience, mathematics, and engineering. It collaborates with institutions such as UC San Diego, the University of Pisa, and MIT. The lab is equipped with advanced imaging tools and has access to Frontera, a leading NSF supercomputer. Outreach includes science nights at local schools and public lectures at the Santa Barbara Museum of Natural History.