Simone Brioschi

Simone Brioschi serves as Assistant Professor in the Department of Pathology & Immunology at Washington University School of Medicine, specializing in Immunobiology within the Colonna Lab.

Education:

• MS in Biotechnology, University of Milano-Bicocca, Italy
• PhD in Biology, University of Freiburg, Germany

Research Focus: Dr. Brioschi investigates CNS-resident immune cells across brain parenchyma, meninges, and choroid plexus. Her work examines cellular origins, developmental mechanisms, and neuron-immune interactions during homeostasis, alongside disease-induced phenotypic changes in neurodegenerative conditions and cancer. Key methodologies include genetic tracking tools and ecosystem analysis of brain macrophages.

Publication Trends: Recent work reveals interdisciplinary convergence between neuroimmunology and cancer research, with emphasis on microglial plasticity in remyelination and T-cell-mediated immunotherapy suppression. Studies consistently explore environmental influences on brain macrophage ecosystems and developmental specification mechanisms.

Awards:

• Alzheimer’s Association Research Grant (AARG-24-1292984)
• 2023 O’Leary Prize Competition

Grants & Mentoring: Secured competitive Alzheimer's Association funding supporting neurodegeneration research. As Assistant Professor, actively mentors graduate students in the Colonna Lab despite no explicitly named advisees in source materials.

Lab Affiliation: Core contributor to the Colonna Lab's neuroimmunology research, focusing on innate immunity mechanisms within central nervous system contexts using advanced genetic and cellular tracking methodologies.