Simon Scheuring

Simon Scheuring, Ph.D., is a Professor of Physiology and Biophysics at Weill Cornell Medical College, Cornell University, with a primary appointment in Anesthesiology. His research focuses on membrane and membrane protein biophysics, structural biology, and single-molecule imaging techniques.

• Techniques: Atomic Force Microscopy (AFM), Cryo-Electron Microscopy (Cryo-EM), Single-Molecule Spectroscopy
• Member of: Physiology, Biophysics and Systems Biology (PBSB)
• Lab Website: bio-afm-lab.com

Dr. Scheuring studies plasma membrane structure and dynamics, emphasizing membrane protein organization and function in eukaryotic cells. His work addresses technical challenges in high-resolution imaging of membrane systems using advanced AFM methodologies, including high-speed AFM for physiological environment imaging. His lab aims to overcome bottlenecks in understanding conformational changes, protein interactions, and supramolecular complexes within native biomembranes.

Recent publications highlight his team's innovations in AFM-based structural biology, membrane protein kinetics, and membrane remodeling mechanisms. The lab develops tools like standardized AFM file formats and investigates medically relevant proteins, including TRPV channels and ESCRT-III homologs.

His lab at 1300 York Avenue (Room E-023) maintains a dedicated website (bio-afm-lab.com) documenting their technical and biological breakthroughs in atomic force microscopy applications.